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Correction to: The mechanism of VCP‑mediated metastasis of osteosarcoma based on cell autophagy and the EMT pathway
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Article
Machine learning for the prediction of postoperative nosocomial pulmonary infection in patients with spinal cord injury
The purpose of this study was to establish the best prediction model for postoperative nosocomial pulmonary infection through machine learning (ML) and assist physicians to make accurate diagnosis and treatmen...
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Article
The role of ferroptosis in chronic intermittent hypoxia-induced cognitive impairment
Obstructive sleep apnea (OSA) is a sleep disorder that may lead to cognitive impairment. The primary pathophysiological feature of OSA is chronic intermittent hypoxia (CIH), but the underlying mechanisms of CI...
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Article
Outcomes of different zero-profile spacers in the treatment of two-level cervical degenerative disk disease
The purpose of this study was to analyze the clinical and radiological outcomes of two different zero-profile spacers (ROI-C and anchor-C) in contiguous two-level ACDF for CDDD patients.
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Article
Role of magnetic resonance imaging features in diagnosing and localization of disc rupture related to cervical spinal cord injury without radiographic abnormalities
A retrospective study.
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Article
Open AccessClinical outcomes and prediction nomogram model for postoperative hemoglobin < 80 g/L in patients following primary lumbar interbody fusion surgery
To analyze the association between different postoperative hemoglobin (Hb) levels and postoperative outcomes in patients who have undergone primary lumbar interbody fusion, and to investigate the risk factors ...
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Article
The mechanism of VCP-mediated metastasis of osteosarcoma based on cell autophagy and the EMT pathway
Study of the molecular mechanisms of metastasis is still the research focus for osteosarcoma (OS) prevention. This study investigates the mechanism of valosin-containing protein (VCP) promoting OS metastasis i...
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Article
Open AccessLRIG2 regulates cell proliferation, migration and apoptosis of osteosarcoma
Osteosarcoma (OS) is one of the malignant bone tumors with strong aggressiveness and poor prognosis. Leucine-rich repeats and immunoglobulin-like domains2 (LRIG2) is closely associated with the poor prognosis ...
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Article
Incidences and reasons of postoperative surgical site infection after lumbar spinal surgery: a large population study
The purpose of this study was to determine the incidences of postoperative acute surgical site infection (SSI) after lumbar spinal surgery and its possible reasons in our hospital during the past 9 years.
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Article
Open AccessAurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway
Autophagy plays an essential role in metastasis of malignancies. Although our studies showed that Aurora-B facilitate pulmonary metastasis in OS, the mechanism of Aurora-B kinase on autophagy and metastasis in...
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Article
Open AccessAnoikis resistant mediated by FASN promoted growth and metastasis of osteosarcoma
The pulmonary metastasis of osteosarcoma (OS) occurs commonly, which resulted from anoikis resistant (AR) of tumor cells as reported by previous studies, but the exact roles of AR in osteosarcoma were not full...
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Article
Open AccessRuthenium-containing supramolecular nanoparticles based on bipyridine-modified cyclodextrin and adamantyl PEI with DNA condensation properties
Exploring safe and highly efficient gene carriers made from biocompatible constituents has great prospects for clinical gene therapy. Here, a supramolecular gene delivery system was readily constructed by asse...
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Article
Open AccessThe anxiolytic-like effects of ginsenoside Rg3 on chronic unpredictable stress in rats
The present study is to evaluate the anxiolytic-like activities underlying ginsenoside Rg3 (GRg3). The anxiolytic-like activities were induced by GRg3 (20 and 40 mg/kg, i.g), evidenced by blocking the decrease...
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Article
Incidence and risk factors for symptomatic spinal epidural haematoma following lumbar spinal surgery
Spinal epidural haematoma (SEH) is a common complication after lumbar spinal decompression surgery, and symptomatic SEH usually causes devastating neurological deficits. Although different risk factors for pos...
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Article
Open AccessClinical characteristics and risk factors for develo** bone metastases in patients with breast cancer
The risk factors for predicting bone metastases in patients with breast cancer are still controversial. Here, a total of 2133 patients with breast cancer, including 327 with bone metastases (15.33%) and 1806 w...
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Article
Open AccessThe risk factors of bone metastases in patients with lung cancer
The risk factors of bone metastasis in patients with lung cancer are still unclear. Here, a retrospective study including a series of consecutive patients who were diagnosed with lung cancer between January 20...
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Article
The effect of screw tunnels on the biomechanical stability of vertebral body after pedicle screws removal: a finite element analysis
Posterior reduction and pedicle screw fixation is a widely used procedure for thoracic and lumbar vertebrae fractures. Usually, the pedicle screws would be removed after the fracture healing and screw tunnels ...
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Article
Open AccessAMD3100 inhibits the migration and differentiation of neural stem cells after spinal cord injury
It was reported that CXCR4 signaling played an important role in the migration and differentiation of endogenous neural stem cells after spinal cord injury (SCI). However, the molecular mechanism of it is stil...
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Article
Open AccessPrognostic performance of pre-treatment NLR and PLR in patients suffering from osteosarcoma
Inflammatory response markers have been proposed to predict the clinical outcomes in various cancers. The aim of this study was to explore the influence of the neutrophil-to-lymphocyte ratio (NLR) and platelet...
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Article
Demethylation-mediated miR-129-5p up-regulation inhibits malignant phenotype of osteogenic osteosarcoma by targeting Homo sapiens valosin-containing protein (VCP)
Previous studies demonstrated that increased Homo sapiens valosin-containing protein (VCP) may be involved in osteosarcoma (OS) metastasis. However, the underlying mechanism of VCP over-expression in OS remains u...
