-
Article
Author Correction: Perioperative toripalimab and chemotherapy in locally advanced gastric or gastro-esophageal junction cancer: a randomized phase 2 trial
-
Article
Perioperative toripalimab and chemotherapy in locally advanced gastric or gastro-esophageal junction cancer: a randomized phase 2 trial
Perioperative chemotherapy is the standard treatment for locally advanced gastric or gastro-esophageal junction cancer, and the addition of programmed cell death 1 (PD-1) inhibitor is under investigation. In t...
-
Article
Open AccessMinor allele of rs55763075 located in MTHFR is associated with the risk of cognitive impairment after anesthesia via modulating miR-34b
This study aimed to investigate the association between cognitive impairment after general anesthesia and rs55763075 polymorphisms. We enrolled and grouped patients undergoing general anesthesia according to t...
-
Article
Isotropic or anisotropic screening in black phosphorous: Can do** tip the balance?
Black phosphorus (BP), a layered van der Waals (vdW) crystal, has unique in-plane band anisotropy and many resulting anisotropy properties such as the effective mass, electron mobility, optical absorption, the...
-
Article
Open AccessImproved SERS Performance and Catalytic Activity of Dendritic Au/Ag Bimetallic Nanostructures Based on Ag Dendrites
Bimetallic nanomaterials, which exhibit a combination of the properties associated with two different metals, have enabled innovative applications in nanoscience and nanotechnology. Here, we introduce the fabr...
-
Article
Open AccessA Tunable Dual-Band and Polarization-Insensitive Coherent Perfect Absorber Based on Double-Layers Graphene Hybrid Waveguide
A suspended monolayer graphene has only about 2.3% absorption rate in visible and infrared band, which limits its optoelectronic applications. To significantly increase graphene’s absorption efficiency, a tuna...
-
Article
Open AccessPES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERα/ERβ protein ratio
PES1, a BRCT domain-containing protein, has been shown to play a role in modulating the balance and ratio between ERα and ERβ protein, which is involved in the occurrence and development of breast and ovarian ...
-
Article
Concomitant high expression of ERα36, GRP78 and GRP94 is associated with aggressive papillary thyroid cancer behavior
Papillary thyroid cancer (PTC) is more common in women than in men. It has been suggested that estrogen may be involved in its development, as has previously been shown for breast, endometrial and ovarian canc...
-
Article
High glucose stimulates cell proliferation and Collagen IV production in rat mesangial cells through inhibiting AMPK-KATP signaling
The present study investigated the putative mechanisms underlying effects of KATP channel on high glucose (HG)-induced mesangial cell proliferation and tissue inhibitors of metalloproteinases (TIMP)-2 and Collage...
-
Article
Open AccessConcomitant high expression of ERα36, EGFR and HER2 is associated with aggressive behaviors of papillary thyroid carcinomas
ERα, ERβ, PR, ERα36, EGFR and HER2 mRNA and protein expression in papillary thyroid carcinoma (PTC) were examined by real time RT-PCR and immunohistochemical staining. The mRNA and protein expression of ERα an...
-
Article
Open AccessCorrection: Corrigendum: Full Valley and Spin Polarizations in Strained Graphene with Rashba Spin Orbit Coupling and Magnetic Barrier
Scientific Reports 6: Article number: 21590; published online: 22 February 2016; updated: 23 January 2017 This Article contains errors in Reference 15 which was incorrectly given as: Song, Y., Zhai, F. & Guo, ...
-
Article
Open AccessFull Valley and Spin Polarizations in Strained Graphene with Rashba Spin Orbit Coupling and Magnetic Barrier
We propose a graphene-based full valley- and spin-polarization device based on strained graphene with Rashba spin orbit coupling and magnetic barrier. The underlying mechanism is the coexistence of the valley ...
-
Article
Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation
An increasingly high occurrence of bone metastases in hepatocellular carcinoma (HCC) patients highlights the importance of fundamental research on HCC bone metastasis, which has been limited in its success due...
-
Article
Thermodynamic Analysis of G-M/J-T Helium Refrigeration Cycle for a Cryoadsorption Test Facility
A cryoadsorption test facility is develo** for upgrade the cryopump of EAST neutral beam injector. To provide an optional cryogenic supply plan for the test facility, a Gifford-McMahon (G-M)/Joule-Thomson (J...
-
Article
Oxidative damage in the kidney and brain of mice induced by different nano-materials
With the rapid development of nanotechnology, nanomaterials have been used in numerous fields. However, these nanomaterials could also result in risk for human and environmental health. To make a comparison of...
-
Article
Native QRS narrowing reflects electrical reversal and associates with anatomical reversal in cardiac resynchronization therapy
Abbreviation of paced QRS duration has been taken as electrical resynchronization imposed by cardiac resynchronization therapy (CRT). However, little is known about alteration in native QRS duration and its co...
-
Article
Expression of TGF-β1, SNAI1 and MMP-9 is associated with lymph node metastasis in papillary thyroid carcinoma
TGF-β1, SNAI1 and MMP-9 are implicated in tumor invasion and metastasis. The purpose of this study was to examine TGF-β1, SNAI1 and MMP-9 expression in papillary thyroid carcinoma (PTC), and to assess associat...
-
Article
Experimental Results of Ion Beam Extraction of High-Current Ion Source for EAST Neutral Beam Injector
The first campaign of ion beam extraction tests are completed for EAST NBI high current ion source. The hydrogen ion beam with beam voltage of 80 keV is extracted from tetrode accelerator system. During the ex...
-
Article
Open AccessLow expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma
Protein tyrosine kinase 6 (PTK6), also known as breast tumor kinase (Brk), was a nonreceptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. The deregulated expression of PTK6 was o...
-
Article
Expression and clinical significance of SIAH in laryngeal squamous cell carcinoma
SIAH is widely expressed in lot of kinds of tumors. It plays a significant role in human cancer, but its clinicopathologic and prognostic significance in laryngeal squamous cell carcinoma (LSCC) has not yet be...
