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Article
Open AccessCircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma
The oncogenic role of circRNA in cancers including esophageal cancer (EC) has been well studied. However, whether and how circRNAs are involved in cancer cell metabolic processes remains largely unknown. Here,...
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Chapter and Conference Paper
Reliability Analysis of Trip** Solenoid Valve Power System Based on Dynamic Fault Tree and Sequential Monte Carlo
Trip solenoid valve is an important device in the steam turbine protection system. Aiming at the problem of trip** solenoid valve malfunction caused by the action of the dual power switching device in the tr...
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Article
Open AccessTransurethral seminal vesiculoscopy for intractable hematospermia: experience from 144 patients
to describe the methodology of transurethral seminal vesiculoscopy and the anatomy of the area of the verumontanum, and to determine the safety of this procedure, especially in terms of postoperative complicat...
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Article
Forecasting solar irradiation based on influencing factors determined by linear correlation and stepwise regression
Determination of the factors influencing solar irradiation plays an important role in the performance of a prediction model based on machine learning techniques. This study compared the results obtained using ...
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Chapter and Conference Paper
Off-Line Performance Calculating Software of the Secondary Loop Thermal System in AP1000 Nuclear Power Plant
The thermal system of secondary loop in nuclear unit is a concentrated expression of thermal performance of the plant. Calculating and Analysis the thermal system of secondary loop is an important project in t...
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Article
Open AccessTherapeutic efficacy of a novel humanized antibody-drug conjugate recognizing plexin-semaphorin-integrin domain in the RON receptor for targeted cancer therapy
Antibody-drug conjugates (ADCs) targeting the RON receptor, a tumorigenic factor contributing to cancer malignancy, has been considered as a novel strategy for cancer therapy. Here we describe a humanized anti...
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Article
The oncoprotein HBXIP competitively binds KEAP1 to activate NRF2 and enhance breast cancer cell growth and metastasis
The nuclear factor E2-related factor 2 (NRF2)-Kelch-like ECH-associated protein 1 (KEAP1) signaling cascades is a key transcriptional pathway governing cellular oxidative stress and tumor development. Mammalia...
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Article
Open AccessCorrection to: Therapeutic efficacy, pharmacokinetic profiles, and toxicological activities of humanized antibody-drug conjugate Zt/g4-MMAE targeting RON receptor tyrosine kinase for cancer therapy
Following publication of the original article [1], the author reported two errors in the authors affiliations:
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Article
Open AccessTherapeutic efficacy, pharmacokinetic profiles, and toxicological activities of humanized antibody-drug conjugate Zt/g4-MMAE targeting RON receptor tyrosine kinase for cancer therapy
Aberrant expression of the RON receptor tyrosine kinase is a pathogenic feature and a validated drug target in various types of cancers. Currently, therapeutic antibodies targeting RON for cancer therapy are u...
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Chapter and Conference Paper
Applications of Data Mining in Conventional Island of Nuclear Power Plant
With the application of digital control system and field-bus technology in nuclear power plant, the production data has the trend of explosive growth. For the large amount of production data with the character...
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Article
Effect of solution treatment on the martensitic transformation behavior of a Ni43Co7Mn39Sn11 polycrystalline alloy
The effect of solution treatment on the martensitic transformation behavior of a Ni43Co7Mn39Sn11 polycrystalline alloy fabricated by an arc melting method was investigated by scanning electron microscopy (SEM), e...
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Article
Open AccessTransciptome analysis reveals flavonoid biosynthesis regulation and simple sequence repeats in yam (Dioscorea alata L.) tubers
Yam (Dioscorea alata L.) is an important tuber crop and purple pigmented elite cultivar has recently become popular because of associated health benefits. Identifying candidate genes responsible for flavonoid bio...
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Article
Genetic diversity analysis of yams (Dioscorea spp.) cultivated in China using ISSR and SRAP markers
Yam (Dioscorea spp.) is widely cultivated in China and many landraces are maintained by local farmers. However, there is little information available about their diversity and species identity. In this study, int...
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Article
A time discontinuous Galerkin finite element method for generalized thermo-elastic wave analysis, considering non-Fourier effects
Generalized thermo-elastic theory, which is based on the non-Fourier theory, indicates that there is a time delay between the heat flux vector and the temperature gradient. At present, the traditional numerica...
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Article
One-pot synthesis of magnetic γ-Fe2O3 nanoparticles in ethanol-water mixed solvent
Maghemite (γ-Fe2O3) nanoparticles were synthesized via a low-temperature solution-based method using ferric chloride hexahydrate and ferrous chloride tetrahydrate as precursors in the mixed solvent of ethanol and...
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Chapter and Conference Paper
Comprehensive Evaluation for HE Based Contrast Enhancement Techniques
The principle of image enhancement is based on increasing the contrast between adjacent pixels, enabling viewers to visually perceive images with greater detail in the textures and edges. Many contrast enhance...
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Article
Secretion of human interferon-β 1b by recombinant Lactococcus lactis
Interferon-β has anti-viral, anti-proliferation and multifunctional immunomodulatory activities and shows promising clinical effects for treatment of inflammatory disorders. The recombinant human interferon-β (hu...
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Article
Principles and realizations of FBG wavelength tuning with elastic beams
The general principles and realizations of FBG wavelength tuning with elastic beams are proposed and demonstrated. Theories and experiments show that when displacement at the center point of simple beams, defl...
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Article
A Computational Method for Interval Mixed Variable Energy Matrices in Precise Integration
To solve the Riccati equation of LQ control problem, the computation of interval mixed variable energy matrices is the first step. Taylor expansion can be used to compute the matrices. According to the analogy...
