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Article
Skin-on-a-Chip Coupled with a Rapid Inflammation Detection System for Cosmetic Ingredient Screening
The skin is the largest organ in the human body, and the physical and chemical factors from which human skin suffers make the human body prone to allergic and inflammatory reactions. The animal testing that ha...
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Article
Open AccessMiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway
Micro RNAs (miRs) have been implicated in various tumorigenic processes. Osteosarcoma (OS) is a primary bone malignancy seen in adolescents. However, the mechanism of miRs in OS has not been fully demonstrated...
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Article
The first-principles study on electrochemical performance, mechanical properties, and lithium-ion migration of LiFePO4 modified by do** with Co and Nb
The LiFePO4 cathode material possesses a low diffusion coefficient and exhibits poor electronic conductivity, respectively due to its uniaxial ion channel and inherent semiconductor properties. To address these l...
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Article
Open AccessCurrent Status and Perspectives of Dual-Atom Catalysts Towards Sustainable Energy Utilization
The advancement and current status of dual-atom catalysts are reported.
The synergistic effects exhibited by recent dual-at...
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Article
First-principles study on LiMn0.5Fe0.5PO4 do** to decrease the Jahn-Teller effect
Transition metal Mn ions are highly promising cathode dopant materials. Due to the introduction of Mn ions, as lithium ions are deintercalated, Mn2+ will be transformed into Mn3+. This situation will lead to a se...
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Article
Open AccessThe new clinical classification of metastatic spinal malignancies serves as a vital reference for surgical management: a retrospective case-control study
It is commonly accepted that surgical treatment is an essential component of the comprehensive management of metastatic spinal malignancies. However, up until now, the clinical classification of metastatic spi...
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Article
First-Principles Calculation Study on the Structure and Electrochemical Properties of Nb- and V-Doped Ni-Rich Ternary (NCM911) Cathode Materials
Nickel-rich ternary layered cathodes for lithium-ion batteries are promising and widely used materials, with high energy density and discharge capacity. However, nickel-rich cathodes present serious mixing and...
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Article
Development of a novel vasculogenic mimicry-associated gene signature for the prognostic assessment of osteosarcoma patients
Osteosarcoma (OS) is a form of primary bone malignancy associated with poor prognostic outcomes. Recent work has highlighted vasculogenic mimicry (VM) as a key mechanism that supports aggressive tumor growth. ...
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Article
Open AccessEfficacy and safety of corticosteroids, hyaluronic acid, and PRP and combination therapy for knee osteoarthritis: a systematic review and network meta-analysis
There are many injectable treatments for knee osteoarthritis with different characteristics and effects, the aim is to understand which one can lead to better and safer results.
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Article
Open Access‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion
In recent years, researchers have proposed a number of adjuvant methods for extended curettage of giant cell tumors of the bone. However, various schemes have significant differences in efficacy and safety. Th...
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Article
SP/5-HT functional cross-talk in melanin biosynthesis: interaction between NK1R and 5-HT2AR
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Article
Open AccessAssociation of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer
Mitochondria determine the physiological status of most eukaryotes. Mitochondrial dynamics plays an important role in maintaining mitochondrial homeostasis, and the disorder in mitochondrial dynamics could aff...
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Chapter and Conference Paper
Study on the Influence of Seasonal Factors on the Performance of Oil Tank Grounding System
The performance of the grounding system directly determines the safe and reliable operation of the oil tank. In cold temperate zone, the design and construction of oil tank grounding system are particularly im...
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Chapter and Conference Paper
SimpleDG: Simple Domain Generalization Baseline Without Bells and Whistles
We present a simple domain generalization baseline, which wins second place in both the common context generalization track and the hybrid context generalization track respectively in NICO CHALLENGE 2022. We v...
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Article
Open AccessTranscriptomics and metabolomics reveal changes in the regulatory mechanisms of osteosarcoma under different culture methods in vitro
Recently, increasing attention has been drawn to the impact of the tumor microenvironment (TME) on the occurrence and progression of malignant tumors. A variety of 3D culture techniques have been used to simul...
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Article
In situ one-step synthesis of CuInS2 thin films with different morphologies and their optical properties
CuInS2 (CIS) thin films with petal-like nanostructures were synthesized in situ on copper substrates through a facile, one-step solvothermal method using InCl3 and thioacetamide ethylene glycol solution. In order...
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Article
Open AccessPeriostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway
Silencing of the periostin gene (POSTN) can inhibit the biological process of several different cancers, and this inhibition may be related to down-regulation of PI3K/AKT signaling. However, the effect of POSTN o...
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Article
Open AccessIdentification of differential proteomics in Epstein-Barr virus-associated gastric cancer and related functional analysis
Epstein-Barr virus-associated gastric cancer (EBVaGC) is the most common EBV-related malignancy. A comprehensive research for the protein expression patterns in EBVaGC established by high-throughput assay rema...
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Article
Open AccessSurveillance of West Nile virus infection in Kashgar Region, **njiang, China, 2013–2016
West Nile virus (WNV) was first isolated in mainland China from mosquitoes in Jiashi County, Kashgar Region, **njiang in 2011, following local outbreaks of viral meningitis and encephalitis caused by WNV. To e...
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Article
Open AccessExosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis
Circular RNAs (circRNAs) can act as vital players in osteoarthritis (OA). However, the roles of circRNAs in OA remain obscure. Herein, we explored the roles of exosomal circRNA bromodomain and WD repeat domain...
