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    Article

    Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

    Cytotoxic T cells are necessary and sufficient for the development of alopecia areata in mice, while JAK inhibition promotes regrowth of hair in patients and mice with established disease.

    Luzhou **ng, Zhenpeng Dai, Ali Jabbari, Jane E Cerise, Claire A Higgins… in Nature Medicine (2014)

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    Article

    Fas ligand–mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity

    Tumor-associated ligands of the activating NKG2D receptor can effectively stimulate T cell responses at early but not late stages of tumor growth. In late-stage human tumor settings, we observed MIC-driven pro...

    Veronika Groh, Kimberly Smythe, Zhenpeng Dai, Thomas Spies in Nature Immunology (2006)