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Article
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
Cytotoxic T cells are necessary and sufficient for the development of alopecia areata in mice, while JAK inhibition promotes regrowth of hair in patients and mice with established disease.
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Article
Fas ligand–mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity
Tumor-associated ligands of the activating NKG2D receptor can effectively stimulate T cell responses at early but not late stages of tumor growth. In late-stage human tumor settings, we observed MIC-driven pro...