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Article
Open AccessRemoval of leftover feed shapes environmental microbiota and limits houseflies-mediated dispersion of pathogenic bacteria in sow breeding farms
Intensive swine breeding industry generates a complex environment where several microbial interactions occur and which constitutes a challenge for biosafety. Ad libitum feeding strategies and low levels of man...
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Article
Excessive dietary L-tryptophan regulated amino acids metabolism and serotonin signaling in the colon of weaning piglets with acetate-induced gut inflammation
L-Tryptophan (Trp) was shown to improve the gut barrier and growth of weaning piglets. However, whether excessive dietary Trp regulates amino acids (AAs) metabolism and gut serotonin (5-HT) homeostasis in pigl...
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Article
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice
The E2 promoter binding factor 1 (E2F1) and the Wnt/β-catenin signaling are crucial in regulating metabolic homeostasis including obesity. The β-catenin interacting protein 1 (CTNNBIP1), also known as the inhi...
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Article
Tryptophan regulates bile and nitrogen metabolism in two pig gut lactobacilli species in vitro based on metabolomics study
Research has demonstrated that tryptophan (Trp) regulated the composition and metabolism of the gut microbiota. However, the detailed mode of action of Trp on the metabolism of intestinal commensal lactobacill...
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Article
Glycine regulates mucosal immunity and the intestinal microbial composition in weaned piglets
Glycine is an amino acid with a diverse array of health benefits regarding metabolism, immunity, and development. The aim of this study was to test the hypothesis that glycine supplementation alters the intest...
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Article
Dietary l-arginine supplementation of tilapia (Oreochromis niloticus) alters the microbial population and activates intestinal fatty acid oxidation
Currently, little is known about the function of l-arginine in the homeostasis of intestinal lipid metabolism. This study was conducted to test the hypothesis that dietary l-arginine supplementation may alter int...
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Article
Protective effects of glycine against lipopolysaccharide-induced intestinal apoptosis and inflammation
Intestinal dysfunction is commonly observed in humans and animals. Glycine (Gly) is a functional amino acid with anti-inflammatory and anti-apoptotic properties. The objective of this study was to test the pro...
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Chapter
Amino Acids in Microbial Metabolism and Function
(AAs) not only serve as building blocks for protein synthesis in microorganisms but also play important roles in , survival, inter-species crosstalk, and virulence. Different AAs have their in microbes of ...
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Article
On transitioning from PID to ADRC in thermal power plants
This paper focuses on the recent progress in the adoption of active disturbance rejection control (ADRC) in thermal processes as a viable alternative to proportional–integral–derivative (PID), especially in co...
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Chapter
Amino Acids in Endoplasmic Reticulum Stress and Redox Signaling
Proteins are the chains of amino acids linked via peptide bonds. In cells, newly synthesized proteins are modified and folded in the endoplasmic reticulum (ER) and matured to be functional proteins before they...
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Article
Open AccessDietary L-arginine supplementation reduces lipid accretion by regulating fatty acid metabolism in Nile tilapia (Oreochromis niloticus)
Excessive white fat accumulation in humans and other animals is associated with the development of multiple metabolic diseases. It is unknown whether dietary L-arginine supplementation reduces lipid deposition in...
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Article
Effects of maternal l-proline supplementation on inflammatory cytokines at the placenta and fetus interface of mice
Dietary l-proline (proline) supplementation during gestation enhances fetal survival and placental development in mice. The objective of the present study was to test the hypothesis that this beneficial effect of...
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Chapter
Epithelial Dysfunction in Lung Diseases: Effects of Amino Acids and Potential Mechanisms
Lung diseases affect millions of individuals all over the world. Various environmental factors, such as toxins, chemical pollutants, detergents, viruses, bacteria, microbial dysbiosis, and allergens, contribut...
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Article
S100A4 promotes inflammation but suppresses lipid accumulation via the STAT3 pathway in chronic ethanol-induced fatty liver
S100A4, a member of the S100 calcium-binding protein family, has been identified in a subpopulation of liver macrophages and promotes liver fibrosis via hepatic stellate cell activation. However, the specific ...
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Article
Maternal l-proline supplementation during gestation alters amino acid and polyamine metabolism in the first generation female offspring of C57BL/6J mice
We recently reported that dietary supplementation with l-proline (proline) during gestation improved embryonic survival in C57BL/6J mice. The objective of the present study was to test the hypothesis that the eff...
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Article
Glycine supplementation to breast-fed piglets attenuates post-weaning jejunal epithelial apoptosis: a functional role of CHOP signaling
This study was conducted to test the hypothesis that preweaning glycine supplementation to breast-fed piglets alleviated the post-weaning apoptosis of jejunal epithelium through CHOP signaling. Seven-day-old...
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Protocol
Analysis of Tryptophan and Its Metabolites by High-Performance Liquid Chromatography
Tryptophan is a nutritionally essential amino acid for both humans and animals. Besides acting as a building block for protein synthesis, tryptophan (Trp) and its metabolites are crucial for maintaining neurol...
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Article
Open AccessEndoplasmic reticulum stress-induced apoptosis in intestinal epithelial cells: a feed-back regulation by mechanistic target of rapamycin complex 1 (mTORC1)
Endoplasmic reticulum (ER) stress is associated with multiple pathological processes of intestinal diseases. Despite a critical role of mechanistic target of rapamycin complex 1 (mTORC1) in regulating cellular...
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Article
Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis
Glycine supplementation has been reported to enhance white-fat loss and improve sensitivity to insulin in animals with obesity or type 2 diabetes. However, the underlying mechanisms responsible for the benefic...
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Article
Open AccessS100A4 promotes lung tumor development through β-catenin pathway-mediated autophagy inhibition
Autophagy has emerged as a critical pathway in tumor development. S100A4 plays important roles in tumor metastasis, but its role in regulating autophagy has not been well characterized. In this study, we found...
