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  1. Article

    Open Access

    Linc00239 Facilitates the Progress of Clear Cell Renal Cell Carcinoma via the miR-204-5p/RAB22A Axis

    Long intergenic non-coding RNA 239 (Linc00239) acts as an oncogene in colorectal cancer (CRC), esophageal squamous cell carcinoma, and acute myeloid leukemia cells. However, its role and regulatory mechanisms in ...

    Cheng Cheng, Shuangquan Lin, Anyi Zhu, Zhengdong Hong, Zimin Shi… in Molecular Biotechnology (2024)

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  2. No Access

    Article

    ROCK2-RNA interaction map reveals multiple biological mechanisms underlying tumor progression in renal cell carcinoma

    Renal cell carcinoma (RCC) is the most common form of kidney cancer in adults. Despite new therapeutic modalities, the outcomes for RCC patients remain unsatisfactory. Rho-associated coiled-coil forming protei...

    Zhengdong Hong, Xuexin Chen, Lei Wang, **aocheng Zhou, Haowei He, Gaode Zou… in Human Cell (2023)

  3. Article

    Open Access

    Pazopanib has equivalent anti-tumor effectiveness and lower Total costs than Sunitinib for treating metastatic or advanced renal cell carcinoma: a meta-analysis

    Sunitinib and pazopanib are extensively used as first-line treatment of metastatic renal cell carcinoma (mRCC). We performed this meta-analysis to assess the anti-tumor effectiveness, toxicity, and total costs...

    Huan Deng, Yu Huang, Zhengdong Hong, Xuhui Yuan, Zhi Cao, Yi** Wei… in BMC Cancer (2019)

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  4. No Access

    Article

    Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer

    Elevated expression of matrix metalloproteinases (MMPs) is correlated with invasion and metastasis of colorectal cancer (CRC). Recently, a previous study has suggested that speckle-type POZ protein (SPOP) coul...

    Shouhua Zhang, Juhua **ao, Yong Chai, Zhengdong Hong… in Digestive Diseases and Sciences (2018)