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    Article

    The role of HIF-1α-mediated autophagy in ionizing radiation-induced testicular injury

    Testis, as a key organ for maintaining male fertility, are extremely sensitive to ionizing radiation (IR). IR-induced testicular dysfunction and infertility are common adverse effects of radiation therapy in p...

    Renfeng Xu, Siting Shen, Defan Wang, Jianqing Ye in Journal of Molecular Histology (2023)

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    Expression and clinical significance of the HIF-1a/ET-2 signaling pathway during the development and treatment of polycystic ovary syndrome

    Polycystic ovary syndrome (PCOS) is a major health problem in reproductive-aged women worldwide, but the precise pathogenesis of PCOS remains unclear. Our previous study revealed that hypoxia-inducible factor ...

    Fan Wang, Zhenghong Zhang, Zhaokai Wang, Kaizhuan **ao in Journal of Molecular Histology (2015)