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  1. No Access

    Chapter and Conference Paper

    Dynamic Response Analysis on Tensile Membrane Structure According to the Wind-Rain Interaction Model

    In view of the damage on some tensile membrane structures caused by wind and rain interaction, a study on the dynamic response of tensile membrane structures was analyzed based on the wind-rain interaction mod...

    Zhengchao Wang, Limei Zhang, **peng Liu in Proceedings of the 2nd International Confe… (2024)

  2. No Access

    Article

    The role of HIF-1α-mediated autophagy in ionizing radiation-induced testicular injury

    Testis, as a key organ for maintaining male fertility, are extremely sensitive to ionizing radiation (IR). IR-induced testicular dysfunction and infertility are common adverse effects of radiation therapy in p...

    Renfeng Xu, Siting Shen, Defan Wang, Jianqing Ye in Journal of Molecular Histology (2023)

  3. Article

    Open Access

    Effects and action mechanisms of individual cytokines contained in PRP on osteoarthritis

    Osteoarthritis (OA) is defined as a degenerative joint disease that can affect all tissues of the joint, including the articular cartilage, subchondral bone, ligaments capsule, and synovial membrane. The conve...

    Zhengchao Wang, Pengfei Zhu, Bokai Liao in Journal of Orthopaedic Surgery and Research (2023)

  4. Article

    Open Access

    Contribution of HIF-1α/BNIP3-mediated autophagy to lipid accumulation during irinotecan-induced liver injury

    Irinotecan is a topoisomerase I inhibitor which has been widely used to combat several solid tumors, whereas irinotecan therapy can induce liver injury. Liver injury generally leads to tissue hypoxia, and hypo...

    Congjian Shi, Zhenghong Zhang, Renfeng Xu, Yan Zhang, Zhengchao Wang in Scientific Reports (2023)

  5. Article

    Open Access

    Functional characterization and analysis of transcriptional regulation of sugar transporter SWEET13c in sugarcane Saccharum spontaneum

    Sugarcane is an important crop for sugar production worldwide. The Sugars Will Eventually be Exported Transporters (SWEETs) are a group of sugar transporters recently identified in sugarcane. In Saccharum spontan...

    **uting Hua, Qiaochu Shen, Yihan Li, Dong Zhou, Zhe Zhang in BMC Plant Biology (2022)

  6. Article

    Open Access

    Efficient, biosafe and tissue adhesive hemostatic cotton gauze with controlled balance of hydrophilicity and hydrophobicity

    Cotton gauze is a widely used topical hemostatic material for bleeding control, but its high blood absorption capacity tends to cause extra blood loss. Therefore, development of rapid hemostatic cotton gauze w...

    Huaying He, Weikang Zhou, **g Gao, Fan Wang, Shaobing Wang in Nature Communications (2022)

  7. Article

    Open Access

    Genetic structure and evolutionary diversity of mating-type (MAT) loci in Hypsizygus marmoreus

    The mating compatibility in fungi is generally governed by genes located within a single or two unlinked mating type (MAT) loci. Hypsizygus marmoreus is an edible mushroom in the order Agaricales with a tetrapola...

    Gang Wang, Yuanyuan Wang, Lianfu Chen, Hongbo Wang, Lin Guo, Xuan Zhou in IMA Fungus (2021)

  8. Article

    Open Access

    Genome-wide identification and expression profiling of DREB genes in Saccharum spontaneum

    The dehydration-responsive element-binding proteins (DREBs) are important transcription factors that interact with a DRE/CRT (C-repeat) sequence and involve in response to multiple abiotic stresses in plants. ...

    Zhen Li, Gang Wang, **hui Liu, Zhengchao Wang, Muqing Zhang, Jisen Zhang in BMC Genomics (2021)

  9. Article

    Open Access

    Comparative analysis of sucrose phosphate synthase (SPS) gene family between Saccharum officinarum and Saccharum spontaneum

    Sucrose phosphate synthase (SPS) genes play vital roles in sucrose production across various plant species. Modern sugarcane cultivar is derived from the hybridization between the high sugar content species Sacch...

    Panpan Ma, **ngtan Zhang, Lan** Chen, Qian Zhao, Qing Zhang in BMC Plant Biology (2020)

  10. No Access

    Article

    The anticancer effects and mechanisms of fucoxanthin combined with other drugs

    Fucoxanthin (Fx) is a characteristic carotenoid present in brown seaweed that has been shown to have various benefits, including anticancer effects. In vitro studies demonstrated these various effects, includi...

    Zhengchao Wang, Hongmei Li, Minghao Dong in Journal of Cancer Research and Clinical On… (2019)

  11. No Access

    Article

    Effect of curcumin-loaded nanoparticles on mitochondrial dysfunctions of breast cancer cells

    Curcumin exhibits excellent anticancer and antibacterial activities. However, this compound has poor solubility and lower bioavailability, which limits its therapeutic efficacy. To improve its anticancer effec...

    Yuhua Wang, Zhihui Luo, Zhengchao Wang, Minghai You in Journal of Nanoparticle Research (2018)

  12. No Access

    Article

    Expression and clinical significance of the HIF-1a/ET-2 signaling pathway during the development and treatment of polycystic ovary syndrome

    Polycystic ovary syndrome (PCOS) is a major health problem in reproductive-aged women worldwide, but the precise pathogenesis of PCOS remains unclear. Our previous study revealed that hypoxia-inducible factor ...

    Fan Wang, Zhenghong Zhang, Zhaokai Wang, Kaizhuan **ao in Journal of Molecular Histology (2015)

  13. No Access

    Article

    Transplantation of mesenchymal stem cells into the renal medulla attenuated salt-sensitive hypertension in Dahl S rat

    Adult stem cell deficiency has been implicated in the pathogenic mechanism for various diseases. Renal medullary dysfunction is one of the major mechanisms for the development of hypertension in Dahl salt-sens...

    Jun** Hu, Qing Zhu, Min **a, Tai L. Guo, Zhengchao Wang in Journal of Molecular Medicine (2014)

  14. Article

    Open Access

    Effects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins

    Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesi...

    Zhengchao Wang, Zhenghong Zhang, Yanqing Wu in Experimental & Molecular Medicine (2012)

  15. No Access

    Article

    Phosphodiesterase 4 and compartmentalization of cyclic AMP signaling

    Cyclic AMP (cAMP), as a second messenger, plays a critical role in cellular signaling transduction. However, it is not clear how this apparently identical cAMP signal induces divergent physiological responses....

    ZhengChao Wang, Fang**ong Shi in Chinese Science Bulletin (2007)