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Chapter and Conference Paper
Dynamic Response Analysis on Tensile Membrane Structure According to the Wind-Rain Interaction Model
In view of the damage on some tensile membrane structures caused by wind and rain interaction, a study on the dynamic response of tensile membrane structures was analyzed based on the wind-rain interaction mod...
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Article
The role of HIF-1α-mediated autophagy in ionizing radiation-induced testicular injury
Testis, as a key organ for maintaining male fertility, are extremely sensitive to ionizing radiation (IR). IR-induced testicular dysfunction and infertility are common adverse effects of radiation therapy in p...
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Article
Open AccessEffects and action mechanisms of individual cytokines contained in PRP on osteoarthritis
Osteoarthritis (OA) is defined as a degenerative joint disease that can affect all tissues of the joint, including the articular cartilage, subchondral bone, ligaments capsule, and synovial membrane. The conve...
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Article
Open AccessContribution of HIF-1α/BNIP3-mediated autophagy to lipid accumulation during irinotecan-induced liver injury
Irinotecan is a topoisomerase I inhibitor which has been widely used to combat several solid tumors, whereas irinotecan therapy can induce liver injury. Liver injury generally leads to tissue hypoxia, and hypo...
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Article
Open AccessFunctional characterization and analysis of transcriptional regulation of sugar transporter SWEET13c in sugarcane Saccharum spontaneum
Sugarcane is an important crop for sugar production worldwide. The Sugars Will Eventually be Exported Transporters (SWEETs) are a group of sugar transporters recently identified in sugarcane. In Saccharum spontan...
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Article
Open AccessEfficient, biosafe and tissue adhesive hemostatic cotton gauze with controlled balance of hydrophilicity and hydrophobicity
Cotton gauze is a widely used topical hemostatic material for bleeding control, but its high blood absorption capacity tends to cause extra blood loss. Therefore, development of rapid hemostatic cotton gauze w...
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Article
Open AccessGenetic structure and evolutionary diversity of mating-type (MAT) loci in Hypsizygus marmoreus
The mating compatibility in fungi is generally governed by genes located within a single or two unlinked mating type (MAT) loci. Hypsizygus marmoreus is an edible mushroom in the order Agaricales with a tetrapola...
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Article
Open AccessGenome-wide identification and expression profiling of DREB genes in Saccharum spontaneum
The dehydration-responsive element-binding proteins (DREBs) are important transcription factors that interact with a DRE/CRT (C-repeat) sequence and involve in response to multiple abiotic stresses in plants. ...
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Article
Open AccessComparative analysis of sucrose phosphate synthase (SPS) gene family between Saccharum officinarum and Saccharum spontaneum
Sucrose phosphate synthase (SPS) genes play vital roles in sucrose production across various plant species. Modern sugarcane cultivar is derived from the hybridization between the high sugar content species Sacch...
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Article
The anticancer effects and mechanisms of fucoxanthin combined with other drugs
Fucoxanthin (Fx) is a characteristic carotenoid present in brown seaweed that has been shown to have various benefits, including anticancer effects. In vitro studies demonstrated these various effects, includi...
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Article
Effect of curcumin-loaded nanoparticles on mitochondrial dysfunctions of breast cancer cells
Curcumin exhibits excellent anticancer and antibacterial activities. However, this compound has poor solubility and lower bioavailability, which limits its therapeutic efficacy. To improve its anticancer effec...
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Article
Expression and clinical significance of the HIF-1a/ET-2 signaling pathway during the development and treatment of polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a major health problem in reproductive-aged women worldwide, but the precise pathogenesis of PCOS remains unclear. Our previous study revealed that hypoxia-inducible factor ...
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Article
Transplantation of mesenchymal stem cells into the renal medulla attenuated salt-sensitive hypertension in Dahl S rat
Adult stem cell deficiency has been implicated in the pathogenic mechanism for various diseases. Renal medullary dysfunction is one of the major mechanisms for the development of hypertension in Dahl salt-sens...
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Article
Open AccessEffects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins
Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesi...
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Article
Phosphodiesterase 4 and compartmentalization of cyclic AMP signaling
Cyclic AMP (cAMP), as a second messenger, plays a critical role in cellular signaling transduction. However, it is not clear how this apparently identical cAMP signal induces divergent physiological responses....