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    Article

    Phosphodiesterase 4 and compartmentalization of cyclic AMP signaling

    Cyclic AMP (cAMP), as a second messenger, plays a critical role in cellular signaling transduction. However, it is not clear how this apparently identical cAMP signal induces divergent physiological responses....

    ZhengChao Wang, Fang**ong Shi in Chinese Science Bulletin (2007)

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    Open Access

    Efficient, biosafe and tissue adhesive hemostatic cotton gauze with controlled balance of hydrophilicity and hydrophobicity

    Cotton gauze is a widely used topical hemostatic material for bleeding control, but its high blood absorption capacity tends to cause extra blood loss. Therefore, development of rapid hemostatic cotton gauze w...

    Huaying He, Weikang Zhou, **g Gao, Fan Wang, Shaobing Wang in Nature Communications (2022)

  3. Article

    Open Access

    Contribution of HIF-1α/BNIP3-mediated autophagy to lipid accumulation during irinotecan-induced liver injury

    Irinotecan is a topoisomerase I inhibitor which has been widely used to combat several solid tumors, whereas irinotecan therapy can induce liver injury. Liver injury generally leads to tissue hypoxia, and hypo...

    Congjian Shi, Zhenghong Zhang, Renfeng Xu, Yan Zhang, Zhengchao Wang in Scientific Reports (2023)