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  1. Article

    Open Access

    Macrophages-aPKCɩ-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma

    Recent data indicated that macrophages may mutually interact with cancer cells to promote tumor progression and chemoresistance, but the interaction in cholangiocarcinoma (CCA) is obscure.

    Tao Yang, Zhengdong Deng, Lei Xu, **angyu Li in Journal of Experimental & Clinical Cancer … (2022)

  2. Article

    Open Access

    Downregulation of ASPP2 promotes gallbladder cancer metastasis and macrophage recruitment via aPKC-ι/GLI1 pathway

    Gallbladder cancer (GBC) is a highly malignant bile duct cancer with poor prognosis due to early invasion and metastasis. However, the molecular mechanisms through which GBC cells interact with the tumor micro...

    Li Tian, Zhengdong Deng, Lei Xu, Tao Yang, Wei Yao, Lei Ji, Yun Lu in Cell Death & Disease (2018)