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    Article

    Synthesis, Evaluation of Anti-Toxoplasma gondii Activity in vitro and Molecular Docking of Dihydroartemisinin Derivatives

    In this work, 21 dihydroartemisinin derivatives were synthesized, their chemical structures were characterized by 1H NMR, 13H NMR and high-resolution MS techniques, and anti-Toxoplasma gondii activity in vitro wa...

    Hao Deng, Zheng-Ai Chen, Yin-Sheng Quan, Qing-Kun Shen in Pharmaceutical Chemistry Journal (2022)

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    17β-Estradiol attenuates vascular contraction through inhibition of RhoA/Rho kinase pathway

    We hypothesized that 17β-estradiol attenuates vascular contraction through inhibition of RhoA/Rho kinase pathway. Rat aortic rings were contracted with cumulative addition of U46619, NaF, KCl or PDBu 30 min af...

    Enyue Yang, Su Bun Jeon, Inji Baek in Naunyn-Schmiedeberg's Archives of Pharmaco… (2009)

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    Liquiritin potentiate neurite outgrowth induced by nerve growth factor in PC12 cells

    Neurite outgrowth and neuronal differentiation play a crucial role in the development of the nervous system. Understanding of neurotrophins induced neurite outgrowth was important to develop therapeutic strate...

    Zheng-ai Chen, Jun-Long Wang, Rui-Ting Liu, Jian-** Ren, Li-Qing Wen in Cytotechnology (2009)