2,823 Result(s)

Article

A quantitative cytochemical investigation of osteoclasts and multinucleate giant cells

Quantitative cytochemical, immunocytochemical, autoradiographic and electron cytochemical investigations have been used to compare osteoclasts with multinucleate giant cells that had been freshly obtained from...

M. H. Zheng, J. M. Papadimitriou, G. C. Nicholson in The Histochemical Journal (1991)

Article

Dietary retinol: prevention or promotion of carcinogenesis in humans?

A number of epidemiologic studies have found that ‘vitamin A’ is associated with a reduced risk for human cancers. Dietary vitamin A indices reflect intake of several compounds in the diet including retinol an...

Susan Taylor Mayne, Saxon Graham, Tongzhang Zheng in Cancer Causes & Control (1991)

Article

Time trend and age-period-cohort effects on incidence of esophageal cancer in Connecticut, 1935–89

The purpose of this study was to examine the incidence pattern of esophageal eancer in Connecticut (USA) during the past decades, and to identify components of birth cohort, period, and age as determinants of ...

Tongzhang Zheng, Susan Taylor Mayne, Theodore R. Holford… in Cancer Causes & Control (1992)

Article

Incidence trends for cancers of the breast, ovary, and corpus uteri in urban Shanghai, 1972–89

Incidence data from the Shanghai (People's Republic of China) Cancer Registry were used to assess the temporal trends of three major female cancers during 1972–89. Rates for cancers of the breast, corpus uteri...

Fan **, **ao-Ou Shu, Susan S. Devesa, Wei Zheng… in Cancer Causes & Control (1993)

Article

A cohort study of smoking, alcohol consumption, and dietary factors for pancreatic cancer (United States)

Risk factors for pancreatic cancer were evaluated in a cohort study of 17,633 White men in the United States who responded to a mailed questionnaire in 1966 and were followed-up through 1986 for mortality. Cig...

Wei Zheng, Joseph K. McLaughlin, Gloria Gridley, Erik Bjelke… in Cancer Causes & Control (1993)

Article

Occupation, physical activity, and risk of prostate cancer in Shanghai, People's Republic of China

Based on occupational data for all (n=264) prostate cancer cases diagnosed during 1980–84 in urban Shanghai and on employment information from the 1982 census, standardized incidence ratios (SIR) were calculated ...

Drs Ann W. Hsing, Joseph K. McLaughlin, Dr Wei Zheng… in Cancer Causes & Control (1994)

Article

Environmental and dietary risk factors for nasopharyngeal carcinoma: a case-control study in Zangwu County, Guangxi, China

A case-control study was conducted on 88 incident cases of histologically confirmed undifferentiated nasopharyngeal carcinoma (NPC) in Zangwu County, China, and 176 age- sex- and neighbourhood-matched controls...

YM Zheng, P Tuppin, A Hubert, D Jeannel, YJ Pan, Y Zeng… in British Journal of Cancer (1994)

Article

Malignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site

This study examined time trends and age-period-cohort patterns in the incidence of cutaneous malignant melanoma (CMM) by gender and anatomic site in Connecticut (United States) between 1950 and 1989, using dat...

Ms Ya-Ting Chen, Dr Tongzhang Zheng, Dr Theodore R. Holford… in Cancer Causes & Control (1994)

Article

Dietary cholesterol, fat, and lung cancer incidence among older women: The Iowa Women's Health Study (United States)

To test the hypothesis that a high intake of dietary cholesterol and fat is associated with elevated risks of lung cancer, we analyzed data from a population-based, prospective, cohort study conducted among 41...

Ying Wu, Dr Wei Zheng, Thomas A. Sellers, Lawrence H. Kushi… in Cancer Causes & Control (1994)

Article

Mutations in the glutathione synthetase gene cause 5–oxoprolinuria

5-Oxoprolinuria (pyroglutamic aciduria)^1,2 resulting from glutathione synthetase (GSS) deficiency^3,4 is an inherited autosomal recessive disorder characterized, in its severe form, by massive urinary excretion of...

Zheng-Zheng Shi, Geetha M. Habib, William J. Rhead, William A. Gahl… in Nature Genetics (1996)

Article

The relationship between dietary fat intake and risk of colorectal cancer: evidence from the combined analysis of 13 case-control studies

The objective of this study was to examine the effects of the intakeof dietary fat upon colorectal cancer risk in a combined analysis of datafrom 13 case-control studies previously conducted in populations wit...

Geoffrey R. Howe, Kristan J. Aronson, Enrique Benito… in Cancer Causes & Control (1997)

Article

Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States)

The genes coding for separate isoforms of both the human glutathioneS-transferase class mu and class theta enzymes (GSTM1and GSTT1) arepolymorphic with a variable ethnic distribution. These enzymes detoxifyrea...

Karl T. Kelsey, Margaret R. Spitz, Zheng-Fa Zuo, John K. Wiencke in Cancer Causes & Control (1997)

Article

Nonlinear model for capillary-tissue oxygen transport and metabolism

Oxygen consumption in small tissue regions cannot be measured directly, but assessment of oxygen transport and metabolism at the regional level is possible with imaging techniques using tracer¹⁵O-oxygen for posit...

Zheng Li, Tada Yipintsoi, James B. Bassingthwaighte in Annals of Biomedical Engineering (1997)

Article

Recording of mitochondrial transmembrane potential and volume in cultured rat osteoclasts by confocal laser scanning microscopy

Osteoclasts are multinuclear bone-resorbing cells which contain abundant mitochondria. Morphological studies have suggested that a correlation may exist between mitochondrial concentration and bone resorption ...

H. Fujii, S. H. Cody, U. Seydel, J. M. Papadimitriou… in The Histochemical Journal (1997)

Article

SHORT COMMUNICATION: A rapid method for the assessment of bone architecture by confocal microscopy

Conventional ways of demonstrating and analysing the components of osseous tissue have always been hampered by the difficulty of physically sectioning bone. In this study, we have used Acridine Orange staining...

M. H. Zheng, H. G. Bruining, S. H. Cody, B. Brankov… in The Histochemical Journal (1997)

Article

Evidence that failure of osteoid bone matrix resorption is caused by perturbation of osteoclast polarization

Osteoclasts resorb bone by a complex dynamic process that initially involves attachment, polarization and enzyme secretion, followed by their detachment and migration to new sites. In this study, we postulated...

S. YOVICH, U. SEYDEL, J. M. PAPADIMITRIOU, G. C. NICHOLSON… in The Histochemical Journal (1998)

Article

Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition

Activation of the tyrosine kinase Src potentiates NMDA-receptor currents, which is thought to be necessary for induction of hippocampal long-term potentiation. Although the carboxy(C)-terminal domain of the NR...

F. Zheng, M.B. Gingrich, S.F. Traynelis, P.J. Conn in Nature Neuroscience (1998)

Article

Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen-presenting cells

A major problem associated with adenovirus gene therapy is the T cell-mediated immune response, which is elicited by inoculation of the adenovirus vector and leads to rapid clearance of the virus and loss of t...

Huang-Ge Zhang, Di Liu, Yuji Heike, **Ar Yang, Zheng Wang… in Nature Biotechnology (1998)

Article

Mutations in the gene encoding gap junction protein β-3 associated with autosomal dominant hearing impairment

Hearing impairment is the most commonly occurring condition that affects the ability of humans to communicate ¹ . More than 50%...

Jia-hui **a., Chun-yu Liu, Bei-sha Tang, Qian Pan, Lei Huang… in Nature Genetics (1998)

Article

Contributory presentations/posters

N. Manoj, V. R. Srinivas, A. Surolia, M. Vijayan, K. Suguna… in Journal of Biosciences (1999)