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  1. Article

    Open Access

    FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

    Selectively targeting leukemia stem cells (LSCs) is a promising approach in treating acute myeloid leukemia (AML), for which identification of such therapeutic targets is critical. Increasing lines of evidence...

    **ao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu in Journal of Hematology & Oncology (2023)

  2. No Access

    Article

    Non-canonical phosphorylation of Bmf by p38 MAPK promotes its apoptotic activity in anoikis

    Bmf contributes to the onset of anoikis by translocating from cytoskeleton to mitochondria when cells lose attachment to the extracellular matrix. However, the structural details of Bmf cytoskeleton tethering ...

    Zhe Zhi, Zhenlin Ouyang, Yibo Ren, Ying Cheng, Peijun Liu in Cell Death & Differentiation (2022)

  3. Article

    Open Access

    Publisher Correction: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma

    In the original version of this Article, financial support was not fully acknowledged. The PDF and HTML versions of the Article have now been corrected to include the following: The National Basic Research Pro...

    Shujun Han, Yibo Ren, Wangxiao He, Huadong Liu, Zhe Zhi in Nature Communications (2018)

  4. Article

    Open Access

    ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma

    In human mutant BRAF melanoma cells, the stemness transcription factor FOXD3 is rapidly induced by inhibition of ERK1/2 signaling and mediates adaptive resistance to RAF inhibitors. However, the mechanism unde...

    Shujun Han, Yibo Ren, Wangxiao He, Huadong Liu, Zhe Zhi in Nature Communications (2018)