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  1. Article

    Open Access

    Adipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3

    The use of adipose-derived mesenchymal stromal cell-derived exosomes (ADSC-Exos) may become a new therapeutic method in biomedicine owing to their important role in regenerative medicine. However, the role of ...

    Hengchen Liu, Mingzhao Zhang, Manyu Shi, Tingting Zhang in Stem Cell Research & Therapy (2021)

  2. Article

    Open Access

    Tendon stem cell-derived exosomes regulate inflammation and promote the high-quality healing of injured tendon

    Tendon stem cells (TSCs) have been reported to hold promises for tendon repair and regeneration. However, less is known about the effects of exosomes derived from TSCs. Therefore, we aimed to clarify the heali...

    Mingzhao Zhang, Hengchen Liu, Qingbo Cui, Peilin Han in Stem Cell Research & Therapy (2020)

  3. No Access

    Article

    Tumor necrosis factor-α and transforming growth factor-β1 facilitate differentiation and proliferation of tendon-derived stem cells in vitro

    To investigate the effects of tumor necrosis factor-α (TNF-α) and transforming growth factor-β1 (TGF-β1) on the proliferation and differentiation of tendon-derived stem cells (TDSC).

    Peilin Han, Qingbo Cui, Shulong Yang, Hao Wang, Peng Gao in Biotechnology Letters (2017)

  4. No Access

    Article

    FAK activity is required for HGF to suppress TGF-β1-induced cellular proliferation

    Due to the complex nature of the tendon architecture, the regeneration of these tissues results in the formation of scars. As a direct result of scar formation, the ability of the tendon tissues to function is...

    Zheng Zhao, Yu Sun, Sulong Yang, Qingbo Cui in In Vitro Cellular & Developmental Biology … (2015)

  5. No Access

    Article

    Effect of Young Extrinsic Environment Stimulated by Hypoxia on the Function of Aged Tendon Stem Cell

    Tendon stem cells (TSCs), recently identified as tendon cells, play an important role in maintaining the homeostasis of tendon tissue. Age-related decrease in the function of TSCs has been reported. Recent rep...

    Dapeng Jiang, Zhitao Jiang, Yubo Zhang, Shuai Wang in Cell Biochemistry and Biophysics (2014)