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Article
Open AccessA novel pyroptosis-related gene signature exhibits distinct immune cells infiltration landscape in Wilms’ tumor
Wilms’ tumor (WT) is the most common renal tumor in childhood. Pyroptosis, a type of inflammation-characterized and immune-related programmed cell death, has been extensively studied in multiple tumors. In the...
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Article
Open AccessREC8 regulates neuroblastoma cell proliferation, migration, invasion, and angiogenesis via STAT3/VEGF signaling
Neuroblastoma, one of the most prevalent childhood cancers, is often treated with surgery, radiation, and chemotherapy. However, prognosis and survival are still dismal for children with neuroblastoma at high ...
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Article
Open AccessAdipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3
The use of adipose-derived mesenchymal stromal cell-derived exosomes (ADSC-Exos) may become a new therapeutic method in biomedicine owing to their important role in regenerative medicine. However, the role of ...
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Article
Open AccessCorrection to: Hepatocyte growth factor inhibits TGF-β1-induced myofibroblast differentiation in tendon fibroblasts: role of AMPK signaling pathway
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessTendon stem cell-derived exosomes regulate inflammation and promote the high-quality healing of injured tendon
Tendon stem cells (TSCs) have been reported to hold promises for tendon repair and regeneration. However, less is known about the effects of exosomes derived from TSCs. Therefore, we aimed to clarify the heali...
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Article
Effects of the donor age on proliferation, senescence and osteogenic capacity of human urine-derived stem cells
To study the effects of the donor age on the application potential of human urine-derived stem cells (hUSCs) in bone tissue engineering, by comparing proliferation, senescence and osteogenic differentiation of...
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Article
Tumor necrosis factor-α and transforming growth factor-β1 facilitate differentiation and proliferation of tendon-derived stem cells in vitro
To investigate the effects of tumor necrosis factor-α (TNF-α) and transforming growth factor-β1 (TGF-β1) on the proliferation and differentiation of tendon-derived stem cells (TDSC).
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Article
Open AccessTailored Fano resonance and localized electromagnetic field enhancement in Ag gratings
Metallic gratings can support Fano resonances when illuminated with EM radiation, and their characteristic reflectivity versus incident angle lineshape can be greatly affected by the surrounding dielectric env...
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Article
FAK activity is required for HGF to suppress TGF-β1-induced cellular proliferation
Due to the complex nature of the tendon architecture, the regeneration of these tissues results in the formation of scars. As a direct result of scar formation, the ability of the tendon tissues to function is...
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Article
Optical Studies on VO2 Thin Films
We have been interested in the plasmonic properties of alternative conducting materials to metals, such as conducting oxides, and we have recently expanded our studies to include highly correlated oxides, such...
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Article
Effect of Young Extrinsic Environment Stimulated by Hypoxia on the Function of Aged Tendon Stem Cell
Tendon stem cells (TSCs), recently identified as tendon cells, play an important role in maintaining the homeostasis of tendon tissue. Age-related decrease in the function of TSCs has been reported. Recent rep...
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Article
Hepatocyte growth factor inhibits TGF-β1-induced myofibroblast differentiation in tendon fibroblasts: role of AMPK signaling pathway
The transforming growth factor-β1 (TGF-β1)-induced myofibroblastic differentiation in tendon fibroblasts was thought to be one of the most important features of scar fibrosis formation, which is associated wit...
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Article
HGF inhibits TGF-β1-induced myofibroblast differentiation and ECM deposition via MMP-2 in Achilles tendon in rat
Both myofibroblast differentiation and extracellular matrix (ECM) deposition are essential components of scar formation in tendons, and hepatocyte growth factor (HGF) is reported to prevent fibrogenic response...
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Article
HGF suppresses the production of collagen type III and α-SMA induced by TGF-β1 in healing fibroblasts
The aim of this study was to examine the effectiveness of HGF in blocking TGF-β1-induced collagen III and α-smooth muscle actin (α-SMA) production in rat healing fibroblasts, fibroblasts were obtained from hea...
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Article
Controlling Cell Responses to Cyclic Mechanical Stretching
In most cell culture studies, cells are grown on smooth culture surfaces. Using microfabrication technology, we have developed microgrooved silicone surfaces to grow cells and subject them to repetitive mechan...
