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Article
Novel hemicyanine dyes with a large Stokes shift and strong fluorescence: mitochondrial-targeted imaging
Hemicyanine dyes have a donor-π-acceptor (D-π-A) system that offers potential applications in mitochondrial-targeted analysis. However, there are currently few hemicyanide dyes with good fluorescent properties...
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Article
DyS-IENN: a novel multiclass imbalanced learning method for early warning of tardiness in rocket final assembly process
Establishing an effective early warning mechanism for the rocket final assembly process (RFAP) is crucial for the timely delivery of rockets and the reduction of additional production costs. To solve the unsys...
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Article
The effect of spleen tyrosine kinase inhibitor R406 on diabetic retinopathy in experimental diabetic rats
To investigate the effect of spleen tyrosine kinase (Syk) inhibitor R406 on diabetic retinopathy (DR) in diabetic mellitus (DM) rats.
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Article
Open AccessInhibition of human carboxylesterases by ginsenosides: structure–activity relationships and inhibitory mechanism
Human carboxylesterases (hCES) are key serine hydrolases responsible for the hydrolysis of a wide range of endogenous and xenobiotic esters. Although it has been reported that some ginsenosides can modulate th...
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Article
Open AccessMicrowave assisted synthesis, antifungal activity, DFT and SAR study of 1,2,4-triazolo[4,3-a]pyridine derivatives containing hydrazone moieties
The increasing prevalence of multi-drug resistant fungal infections has encouraged the search for new antifungal agents. Hydrazone derivatives always exhibited diversity activities, including antifungal, anti-...
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Article
Electrophysiological and behavioral responses of Diaphania glauculalis males to female sex pheromone
The aim of this study is to identify the pheromone active component of female moths, Diaphania glauculalis, an important pest of Anthocephalus chinensis in China. The sex pheromone was extracted from sex pheromon...
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Article
Erratum to: Novel mutation c.980_983delATTA compound with c.986C>A mutation of the FRMD7 gene in a Chinese family with X-linked idiopathic congenital nystagmus
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Article
Novel mutation c.980_983delATTA compound with c.986C>A mutation of the FRMD7 gene in a Chinese family with X-linked idiopathic congenital nystagmus
To screen mutations in FERM domain-containing protein 7 (FRMD7) gene in two Chinese families with X-linked idiopathic congenital nystagmus (XLICN).
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Article
Estimation of genetic parameters for growth traits of Japanese flounder Paralichthys olivaceus using an animal model
To estimate genetic parameters of growth traits in Japanese flounder Paralichthys olivaceus, full-sib and half-sib families were produced in three consecutive years at the Beidaihe Central Experiment Station in C...
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Article
Deoxyschisandrin modulates synchronized Ca2+ oscillations and spontaneous synaptic transmission of cultured hippocampal neurons
Deoxyschisandrin is one of the most effective composites of Schisandra chinensis, a famous Chinese medicine widely used as an antistress, anti-aging, and neurological performance-improving herb. In this study, we...
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Article
MEK inhibitor PD98059 acutely inhibits synchronized spontaneous Ca2+ oscillations in cultured hippocampal networks
To investigate the changes in synchronized spontaneous Ca2+ oscillations induced by mitogen-activated protein kinase kinase (MEK) inhibitor PD98059 at different concentrations in cultured hippocampal network.
