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  1. No Access

    Article

    ERK/PKM2 Is Mediated in the Warburg Effect and Cell Proliferation in Arsenic-Induced Human L-02 Hepatocytes

    This study aimed to investigate the potential role of pyruvate kinase M2 (PKM2) and extracellular regulated protein kinase (ERK) in arsenic-induced cell proliferation. L-02 cells were treated with 0.2 and 0.4 ...

    Fanshuo Yin, **n Zhang, Zaihong Zhang, Meichen Zhang… in Biological Trace Element Research (2024)

  2. No Access

    Article

    Association between arsenic (+3 oxidation state) methyltransferase gene polymorphisms and arsenic methylation capacity in rural residents of northern China: a cross-sectional study

    Arsenic is a toxic metal-like element. The toxic reaction of the body to arsenic is related to the ability of arsenic methylation metabolism. As the rate-limiting enzyme of arsenic methylation metabolism, the ...

    Meichen Zhang, Haili Xu, Qun Lou, Zaihong Zhang, **n Zhang… in Archives of Toxicology (2023)

  3. No Access

    Article

    SIRT1/P53 pathway is involved in the Arsenic induced aerobic glycolysis in hepatocytes L-02 cells

    Arsenic is a known human carcinogen. Low doses of arsenic can induce cell proliferation, but the mechanism remains elusive. Aerobic glycolysis, also known as the Warburg effect, is one of the characteristics o...

    Meichen Zhang, Zaihong Zhang, Qun Lou… in Environmental Science and Pollution Resear… (2023)

  4. No Access

    Article

    Modeling Fecal Coliform Bacteria Levels at Gulf Coast Beaches

    This study presents and compares two models for predicting fecal coliform levels at Gulf Coast beaches in Louisiana, USA. One was developed using the artificial neural network (ANN) in MATLAB toolbox and the o...

    Zaihong Zhang, Zhiqiang Deng, Kelly A. Rusch in Water Quality, Exposure and Health (2015)