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    Article

    Nitrated meat products are associated with mania in humans and altered behavior and brain gene expression in rats

    Mania is a serious neuropsychiatric condition associated with significant morbidity and mortality. Previous studies have suggested that environmental exposures can contribute to mania pathogenesis. We measured...

    Seva G. Khambadkone, Zachary A. Cordner, Faith Dickerson in Molecular Psychiatry (2020)

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    Open Access

    Exendin-4 reduces food intake via the PI3K/AKT signaling pathway in the hypothalamus

    Exendin-4 (EX-4), a glucagon-like peptide-1 (GLP-1) receptor agonist, has been shown to reduce food intake and to increase proopiomelanocortin (POMC) gene expression in the hypothalamus. In this study, we examine...

    Yan Yang, Pique P. Choi, Wanli W. Smith, Weijie Xu, Delin Ma in Scientific Reports (2017)