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Article
Open AccessGenome of the Komodo dragon reveals adaptations in the cardiovascular and chemosensory systems of monitor lizards
Monitor lizards are unique among ectothermic reptiles in that they have high aerobic capacity and distinctive cardiovascular physiology resembling that of endothermic mammals. Here, we sequence the genome of t...
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Article
Open AccessOMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps
We present a new method, OMSV, for accurately and comprehensively identifying structural variations (SVs) from optical maps. OMSV detects both homozygous and heterozygous SVs, SVs of various types and sizes, a...
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Article
Open AccessFinished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome
Although the reference human genome sequence was declared finished in 2003, some regions of the genome remain incomplete due to their complex architecture. One such region, 1q21.1-q21.2, is of increasing inter...
