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  1. Article

    Open Access

    Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1

    Chemokines are involved in many pathological responses of the brain. Astrocytes produce various chemokines in brain disorders, but little is known about the factors that regulate astrocytic chemokine productio...

    Yutaka Koyama, Mao Kotani, Tadateru Sawamura in Journal of Neuroinflammation (2013)

  2. No Access

    Article

    The Na+-Ca2+ Exchange Inhibitor KB-R7943 Inhibits High K+-Induced Increases in Intracellular Ca2+ Concentration and [3H]Noradrenaline Release in the Human Neuroblastoma SH-SY5Y

    The effects of the Na+-Ca2+ exchange inhibitor 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea methanesulfonate (KB-R7943) on depolarization-induced Ca2+ signal and [3H]noradrenaline release were examined in S...

    Hiroaki Nakamura, Yasushi Kawasaki, Naohisa Arakawa, Makio Saeki in Neurochemical Research (2000)

  3. No Access

    Article

    Characteristics of Cl-dependentl-[35S]cysteic acid transport into rat brain synaptic membrane vesicles

    Uptake ofl-[35S]cysteic acid (L-CA) in rat synaptic membrane vesicles was investigated. Preincubation with either 10 mMl-glutamic acid (L-Glu), 25 mM L-CA, 10 mMdl-homocysteic acid, or 25 mMdl-2-amino-4-phosphono...

    Yutaka Koyama, Akemichi Baba, Heitaroh Iwata in Neurochemical Research (1990)

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    Chapter

    Neurochemical Characterization of Excitatory Amino Acid Receptors in Hippocampus

    Glutamate and aspartate may be excitatory neurotransmitters within central nervous system (CNS) (6,9). The recent development of specific antagonists has revealed at least three pharmacologically distinct clas...

    Akemichi Baba, Yutaka Koyama, Hiroshi Morimoto, Heitaroh Iwata in The Biology of Taurine (1987)