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Article
Association between aortic thrombi detected using non-obstructive general angioscopy and atrial fibrillation
Atrial fibrillation (AF) is an independent risk factor for stroke and systemic embolism. Cardiogenic and aortogenic emboli are causes of stroke or systemic embolism. Non-obstructive general angioscopy (NOGA) c...
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Article
Open AccessProtective effect of the Impella on the left ventricular function after acute broad anterior wall ST elevation myocardial infarctions with cardiogenic shock: cardiovascular magnetic resonance imaging strain analysis
The clinical efficacy of the Impella for high-risk percutaneous coronary intervention (PCI) and cardiogenic shock remains under debate. We thus sought to investigate the protective effects on the heart with th...
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Article
Evaluation of the incidence, timing, and potential recovery rates of complete atrioventricular block after transcatheter aortic valve implantation: a Japanese multicenter registry study
Data on the accurate onset date and serial changes of the complete atrioventricular block (CAVB) after transcatheter aortic valve implantation (TAVI) are limited. This study aimed to assess the incidence, timi...
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Article
Open AccessPathological findings after third- and second-generation everolimus-eluting stent implantations in coronary arteries from autopsy cases and an atherosclerotic porcine model
Pathological changes after third-generation drug-eluting stent implantation remain unclear. We compared the tissue responses of coronary arteries after the implantation of third-generation abluminal biodegrada...
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Article
Aortic root rupture caused by simultaneous aortic root injection during balloon aortic valvuloplasty in a patient undergoing transcatheter aortic valve implantation
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Article
Importance of combined assessment of skeletal muscle mass and density by computed tomography in predicting clinical outcomes after transcatheter aortic valve replacement
Skeletal muscle mass (SMM) as calculated by computed tomography (CT) is a predictor of all-cause mortality after transcatheter aortic valve replacement (TAVR), but it remains unclear whether using CT-determine...
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Article
Effect of drug-coated balloon angioplasty on in-stent restenotic coronary lesions analyzed with optical coherence tomography and serial coronary artery angioscopy
Drug-coated balloon angioplasty (DCBA) has been recognized for its utility in preventing in-stent re-restenosis (ISR); however, imaging of the neointima immediately after treatment and during follow-up has onl...
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Article
Open AccessA drainage catheter tangled around a closed left atrial appendage
A 70-year-old man underwent cardiac surgery including left atrial appendage closure. A pigtail catheter was inserted into the pericardial sac because of delayed tamponade. Removal of the catheter was planned f...
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Article
Left main coronary malperfusion from acute non-communicating aortic dissection
A 64-year-old man was admitted with sudden back and chest pain. He had undergone aortic valve replacement 5 years earlier. Enhanced computed tomography showed acute type A non-communicating aortic dissection. ...
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Article
Effects of sitagliptin on coronary atherosclerosis evaluated using integrated backscatter intravascular ultrasound in patients with type 2 diabetes: rationale and design of the TRUST study
Patients with diabetes mellitus are at high risk for develo** coronary artery disease (CAD), even if they are treated with statins. Several studies have shown the beneficial effects of dipeptidyl peptidase-4...
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Article
Early and mid-term results of isolated aortic valve replacement for aortic stenosis in octogenarians
As transcatheter aortic valve implantation (TAVI) may become a potential treatment for high-risk patients with aortic stenosis (AS), evaluation of outcomes after open aortic valve replacement (AVR) in elderly ...
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Article
The calcified ascending aorta in aortic valve replacement: surgical strategies and results
Calcification in the ascending aorta may constitute a major problem during aortic valve replacement (AVR). We examined the distributions of calcification and the associated operative strategies.
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Article
Open AccessDifferent actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1
Chemokines are involved in many pathological responses of the brain. Astrocytes produce various chemokines in brain disorders, but little is known about the factors that regulate astrocytic chemokine productio...
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Article
The Na+-Ca2+ Exchange Inhibitor KB-R7943 Inhibits High K+-Induced Increases in Intracellular Ca2+ Concentration and [3H]Noradrenaline Release in the Human Neuroblastoma SH-SY5Y
The effects of the Na+-Ca2+ exchange inhibitor 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea methanesulfonate (KB-R7943) on depolarization-induced Ca2+ signal and [3H]noradrenaline release were examined in S...
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Chapter
L-Glutamate-Induced Swelling of Cultured Astrocytes
Neurotransmission is influenced by various astrocytic functions. One of the more important astrocytic functions is control of the ion composition in extracellular fluid. Changes in astrocytic volume are respon...
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Article
Characteristics of Cl−-dependentl-[35S]cysteic acid transport into rat brain synaptic membrane vesicles
Uptake ofl-[35S]cysteic acid (L-CA) in rat synaptic membrane vesicles was investigated. Preincubation with either 10 mMl-glutamic acid (L-Glu), 25 mM L-CA, 10 mMdl-homocysteic acid, or 25 mMdl-2-amino-4-phosphono...
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Chapter
Neurochemical Characterization of Excitatory Amino Acid Receptors in Hippocampus
Glutamate and aspartate may be excitatory neurotransmitters within central nervous system (CNS) (6,9). The recent development of specific antagonists has revealed at least three pharmacologically distinct clas...