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    No relationship exists between itai-itai disease and TA repeat polymorphisms of the estrogen receptor α gene

    Itai-itai (ouch-ouch) disease is a syndrome accompanied by bone mineral disorders that may be related to oral cadmium exposure. Itai-itai predominantly affects postmenopausal women with a history of multiple ...

    Ahmad Sadewa, Yuri Miyabe, Hisahide Nishio, Chiyo Hayashi… in Archives of Toxicology (2002)