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Article
Dysregulations of amino acid metabolism and lipid metabolism in urine of children and adolescents with major depressive disorder: a case-control study
The mechanisms underlying major depressive disorder (MDD) in children and adolescents are unclear. Metabolomics has been utilized to capture metabolic signatures of various psychiatric disorders; however, urin...
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Article
Open AccessIdentifying plasma metabolic characteristics of major depressive disorder, bipolar disorder, and schizophrenia in adolescents
Major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SCZ) are classified as major mental disorders and together account for the second-highest global disease burden, and half of these pat...
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Article
Open AccessSequenced treatment alternatives to relieve adolescent depression (STAR-AD): a multicentre open-label randomized controlled trial protocol
Adolescent major depressive disorder (MDD) is a prevalent mental health problem with low treatment success rates. Whether fluoxetine or fluoxetine combined with cognitive-behavioural therapy (CBT) is the more ...
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Article
Open AccessPhotomodulation alleviates cellular senescence of aging adipose-derived stem cells
Mesenchymal stem cells (MSCs) therapies are emerging as a promising approach to therapeutic regeneration. Therapeutic persistence and reduced functional stem cells following cell delivery remain critical hurdl...
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Article
When Is Silence Golden? A Meta-analysis on Antecedents and Outcomes of Employee Silence
Recent research on employee silence has grown rapidly, but findings remain quantitatively unsynthesized. This paper presents a comprehensive meta-analysis of antecedents and outcomes associated with employee s...
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Article
Selective N-Alkylation of 2-Amino-4H-chromene-3-carbonitrile Derivatives with Alcohols Catalyzed by AlCl3 Under the Assistance of CH3COOH
A highly efficient and selective N-alkylation reaction of 2-amino-4H-chromene-3-carbonitrile derivatives using various alcohols as alkylation agent were developed in the presence of AlCl3 as a catalyst as well as...
