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Article
Optimal Gear Shift Control of Two-Speed Dual-Clutch Transmission in Electric Vehicle for Smoothness and Friction Loss Reduction
An optimal shift control strategy for electric vehicles with the two-speed dual-clutch transmission is proposed to reduce the vehicle jerk and friction work during gear shift. The dynamic model of the powertra...
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Article
The effectiveness of extended reality on relieving pain after total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials
Patients with total knee arthroplasty (TKA) often suffer from severe postoperative pain, which seriously hinders postoperative rehabilitation. Extended reality (XR), including virtual reality, augmented realit...
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Article
Three-dimensional MFBD-DEM coupling simulation of flexible wire mesh wheel–soil over lunar rough terrain
This paper proposes a comprehensive approach to studying the interaction between wire mesh wheels and rough lunar terrain to enhance the maneuverability and traction of lunar rovers. The study involves the cre...
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Article
Impacts of task value belief and relational quality on hMOOC learner satisfaction in the post-pandemic era: The mediating roles of Learner Engagement and Knowledge sharing
Despite the growing importance of MOOCs and their application in face-to-face classes since 2020, driven by the COVID-19 pandemic, existing literature offers limited research on the factors affecting the quali...
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Article
Open AccessAugmented reality-assisted versus conventional total hip arthroplasty: a systematic review and meta-analysis
Extended reality (XR), including virtual reality, augmented reality (AR), and mixed reality, has been used to help achieve accurate acetabular cup placement in total hip arthroplasty (THA). This study aimed to...
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Article
Long Non-coding RNA SNHG1 Suppresses the Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by Binding with HMGB1
Osteoporosis (OP) has a significant detrimental impact on the health of the elder. Long-term clinical effectiveness of current drugs used for OP treatment is limited. Therefore, it is very important to explore...
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Article
Early surgery within 48 h was associated with reduced perioperative blood loss and red blood cell transfusion requirements in older patients with hip fracture: a retrospective study
The aim of this study was to analyze the relationship between the timing of surgery and perioperative blood loss, red blood cell (RBC) transfusion rate, and RBC transfusion volume in older patients with hip fr...
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Article
Knockdown of NF-κB activating protein promotes pancreatic cancer growth and metastasis through mTOR signaling pathway
NF-κB activating protein (NKAP) acts as a transcriptional suppressor in the Notch signaling pathway, It plays a role in hematopoiesis maintenance, immune cell development, maturation, and functional competency...
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Article
Open AccessRPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy
Abnormal biogenesis and ribosome free function of ribosomal proteins (RPs) is important for tumorgenesis and development. Ribosomal protein L11 (RPL11) is a component of ribosomal 60 S large subunit with diffe...
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Article
Open AccessBioinformatics analysis of prognostic value and immunological role of MeCP2 in pan-cancer
Methyl-CpG-binding protein 2(MeCP2) is an important epigenetic regulatory factor that promotes many tumor developments, such as liver cancer, breast cancer, and colorectal cancer. So far, no pan-cancer analysi...
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Article
Comparison of a fractional 2940-nm Er:YAG laser and 5% amorolfine lacquer combination therapy versus a 5% amorolfine lacquer monotherapy for the treatment of onychomycosis: a randomized controlled trial
Onychomycosis is a fungal infection of the nail. The aim of this randomized controlled clinical trial was to compare the efficacy of 2940-nm Er:YAG laser treatment combined with a 5% amorolfine lacquer versus ...
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Article
Comparative Study of Cytokine Levels in Different Respiratory Samples in Mild-to-Moderate AECOPD Patients
Matrix metalloproteinase-12 (MMP-12) and Tissue inhibitor of metalloproteinase-4 (TIMP-4) play important roles in the pathophysiology of chronic obstructive pulmonary disease (COPD). Subjects of many previous ...
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Article
High Serum Fractalkine/CX3CL1 in Patients with Chronic Obstructive Pulmonary Disease: Relationship with Emphysema Severity and Frequent Exacerbation
The purpose of this study was to investigate the relationship between serum fractalkine (CX3CL1/FKN) level and the multi-slice spiral computed tomography (MSCT) emphysema index in Chinese patients with chronic...
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Article
Modeling and simulation of revolute clearance joint with friction using the NURBS-based isogeometric analysis
In this work, the revolute clearance joint problem is discussed within the framework of isogeometric analysis (IGA). A unified geometric and analysis model for the clearance joint is proposed based on the mult...
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Article
Nonlinear dynamic model of air spring with a damper for vehicle ride comfort
The air spring component with a damper inside is widely used in the commercial vehicle as a vibration isolator. The nonlinear dynamics of the air spring component is important for full vehicle ride comfort eva...
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Article
Dynamic computation of flexible multibody system with uncertain material properties
Based on the theory of Absolute Nodal Coordinate Formulation, this paper proposes a new dynamic computation method to solve the flexible multibody system with uncertain material properties (Young’s modulus and...
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Chapter and Conference Paper
Modeling and Multi-Objective Optimization of Double Suction Centrifugal Pump Based on Kriging Meta-models
This paper presents the multi-objective optimization problem of double suction centrifugal pump using Kriging meta-model. A set of double suction centrifugal pumps with various blade shapes were numerically si...
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Chapter and Conference Paper
The Interval Uncertain Optimization Strategy Based on Chebyshev Meta-model
This paper proposes a new design optimization method for structures subject to uncertainty. Interval model is used to account for uncertainties of uncertain-but-bounded parameters. It only requires the determi...
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Article
Simulation method of sliding snow load on roofs and its application in some representative regions of China
Sliding snow load on roofs is an important issue. Thus, a simulation method to calculate the sliding snow load on roofs is developed in this paper. Firstly, based on previous mass- and energy-balance models, a...
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Chapter and Conference Paper
Multi-Domain Modeling and Simulation of Automotive Air Conditioning System Based On Modelica
The automotive air conditioning (AC) systems are complex systems where two-phase flow, pneumatic, mechanical and electrical components are coupled. Such systems coupled with various physical domains have great...
