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Article
A Novel Guidance Algorithm for Underactuated Ship Path-Following Control Based on Marine Practice
Ship path-following is necessary for both manned and unmanned ships. During ship navigation, the planned route consists of several waypoints rather than being an arbitrary curve. This makes it essential that p...
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Article
Essential roles of S100A10 in Toll-like receptor signaling and immunity to infection
Toll-like receptors (TLRs) are key pattern recognition receptors that mediate innate immune responses to infection. However, uncontrolled TLR activation can lead to severe inflammatory disorders such as septic...
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Article
Open AccessBCL3 Expression Is a Potential Prognostic and Predictive Biomarker in Acute Myeloid Leukemia of FAB Subtype M2
Although the implication of BCL3 has been disclosed in human chronic lymphocytic leukemia as well as other solid tumors, the diagnostic and prognostic of BCL3 expression in acute myeloid leukemia (AML) remains la...
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Article
Open AccessAberrant host immune response induced by highly virulent PRRSV identified by digital gene expression tag profiling
There was a large scale outbreak of the highly pathogenic porcine reproductive and respiratory syndrome (PRRS) in China and Vietnam during 2006 and 2007 that resulted in unusually high morbidity and mortality ...
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Article
Characterization and transcriptional regulation analysis of the porcine TNFAIP8L2 gene
Tumor necrosis factor alpha-induced protein 8-like 2 (TNFAIP8L2) is a new member of the tumor necrosis factor-α-induced protein 8 (TNFAIP8) family that functions as an important factor in the maintenance of immun...
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Article
Open AccessProteome changes of lungs artificially infected with H-PRRSV and N-PRRSV by two-dimensional fluorescence difference gel electrophoresis
Porcine reproductive and respiratory syndrome with PRRS virus (PRRSV) infection, which causes significant economic losses annually, is one of the most economically important diseases affecting swine industry w...
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Article
Open AccessA deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/β-catenin signaling pathway
MicroRNAs (miRNAs) are a large class of tiny non-coding RNAs (~22-24 nt) that regulate diverse biological processes at the posttranscriptional level by controlling mRNA stability or translation. As a molecular...
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Article
Molecular cloning, expression patterns and subcellular localization of porcine TMCO1 gene
The product of transmembrane and coiled-coil domains 1 (TMCO1) gene is a member of DUF841 superfamily of several eukaryotic proteins with unknown function. The partial DNA sequence of porcine TMCO1 was first clon...