9 Result(s)
within
Yun-Fei Yuan
Oncology
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Article
Open AccessInfluence of AFP on surgical outcomes in non-B non-C patients with curative resection for hepatocellular carcinoma
To study the clinical and prognostic features of non-B non-C alpha-fetoprotein (AFP)(-)-hepatocellular carcinoma (HCC) (NBNC-AFP(-)-HCC) and the relationship between the prognostic features of HCC and hepatiti...
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Article
Open AccessPARP inhibitor Olaparib overcomes Sorafenib resistance through resha** the pluripotent transcriptome in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common human malignancies worldwide with very poor prognosis. Resistance to targeted therapeutic drugs such as sorafenib remains one of the major challenges in...
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Article
Histopathological growth patterns correlate with the immunoscore in colorectal cancer liver metastasis patients after hepatectomy
Various scoring systems have been proposed to predict the postoperative prognosis of colorectal liver metastasis (CRLM), including the clinical risk score (CRS), the immunoscore and so on. Recently, histopatho...
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Article
Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway
The poorly differentiated hepatocellular carcinoma (HCC) cells are usually characterized by immature hepatic progenitor cell-like properties, such as enhanced self-renewal ability, resistance to chemotherapeut...
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Article
The Immunoscore system predicts prognosis after liver metastasectomy in colorectal cancer liver metastases
The Immunoscore was initially established to evaluate the prognosis of stage I/II/III colorectal cancer patients. However, the feasibility of the Immunoscore for the prognosis of colorectal cancer liver metast...
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Article
Open AccessPathologic response after preoperative therapy predicts prognosis of Chinese colorectal cancer patients with liver metastases
Pathologic response is evaluated according to the extent of tumor regression and is used to estimate the efficacy of preoperative treatment. Several studies have reported the association between the pathologic...
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Article
Open AccessImpact of oral anti–hepatitis B therapy on the survival of patients with hepatocellular carcinoma initially treated with chemoembolization
Most hepatocellular carcinomas (HCC) develop in a background of underlying liver disease including chronic hepatitis B. However, the effect of antiviral therapy on the long-term outcome of patients with hepati...
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Article
Checkpoint kinase 1 is negatively regulated by miR-497 in hepatocellular carcinoma
Checkpoint kinase 1 (CHEK1) is an evolutionarily conserved Ser/Thr kinase, which mediates cell-cycle arrest after DNA damage, and we previously reported that CHEK1 was overexpressed and associated with poor pr...
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Article
Randomized study of chemoembolization as an adjuvant therapy for primary liver carcinoma after hepatectomy
From April 1990 to December 1993, 140 patients were recruited to a randomized study to evaluate transcatheter hepatic arterial chemoembolization (TACE) as an adjuvant therapy for primary liver carcinoma after ...
