44 Result(s)

Article

Insulin stimulation of glucose and amino acid transport in mouse fibroblasts with elevated membrane microviscosity

Basal and insulin-stimulated transport of 2-deoxy glucose and of α-aminoisobutyric acid in mouse 3T3 fibroblasts were modulated by increasing the lipid microviscosity of the cell plasma membrane. The kinetics ...

I. Yuli, S. Incerpi, P. Luly, M. Shinitzky in Experientia (1982)

Article

Activation of p53 transcriptional activity by 1,10-phenanthroline, a metal chelator and redox sensitive compound

p53, a tumor suppressor gene, functioning as a transcription factor, has been recently shown in a cell free system to be subject to redox (reduction/oxidation) regulation. Oxidants or metal chelating reagents ...

Yi Sun, Junhui Bian, Yuli Wang, Christine Jacobs in Oncogene (1997)

Article

Induction of apoptosis by Elk-1 and ΔElk-1 proteins

Elk-1, an ets related gene codes for at least two splice variants Elk-1, which regulates c-fos transcription and ΔElk-1, both of which function as transcriptional activators. To investigate the role of Elk-1 and ...

Ningsheng Shao, YuLi Chai, Jian-qi Cui, Nan Wang, Kartik Aysola… in Oncogene (1998)

Article

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21^WAF1/CIP1 promoter

Inherited mutations in the breast and ovarian cancer susceptibility gene BRCA1 are associated with high risk for develo** breast and ovarian cancers. Several studies link BRCA1 to transcriptional regulation,...

YuLi Chai, Jian-qi Cui, Ningsheng Shao, E Shyam P Reddy, Veena N Rao in Oncogene (1999)

Article

c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells

Elk-1, a c-Fos protooncogene regulator, which belongs to the ETS-domain family of transcriptional factors, plays an important role in the induction of immediate early gene expression in response to a variety o...

YuLi Chai, Galina Chipitsyna, Jianqi Cui, Boshan Liao, Shuang Liu… in Oncogene (2001)

Article

LFIRE-1/HFREP-1, a liver-specific gene, is frequently downregulated and has growth suppressor activity in hepatocellular carcinoma

We have previously identified several novel genes, which are differentially expressed among human normal liver and hepatocellular carcinomas (HCCs). The full-length liver fibrinogen-related gene-1 (LFIRE-1) cDNA ...

Jun Yan, Yanlin Yu, Nan Wang, Yunchao Chang, Hao Ying, Weizhong Liu, ** He… in Oncogene (2004)

Article

BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers

Breast cancer gene 1 (BRCA1) mutations predispose women to breast and ovarian cancers and men to increased risks for prostate cancer. We have previously showed BRCA1 splice variant BRCA1a/p110 to induce apopto...

C Yuli, N Shao, R Rao, P Aysola, V Reddy, G Oprea-llies, L Lee, J Okoli… in Oncogene (2007)

Article

Correlation of Oxidized Low-Density Lipoprotein and C-Reactive Protein in Patients with Coronary Artery Disease

Yuli Huang, Yanxian Wu, Yunzhao Hu in Cell Biochemistry and Biophysics (2013)

Article

Human amnion mesenchymal stem cells promote proliferation and osteogenic differentiation in human bone marrow mesenchymal stem cells

Human amnion mesenchymal stem cells (HAMSCs) can be obtained from human amniotic membrane, a highly abundant and readily available tissue. HAMSC sources present fewer ethical issues, have low immunogenicity, a...

Yuli Wang, Ying Yin, Fei Jiang, Ning Chen in Journal of Molecular Histology (2015)

Article

A high-throughput platform for stem cell niche co-cultures and downstream gene expression analysis

Stem cells reside in ‘niches’, where support cells provide critical signalling for tissue renewal. Culture methods mimic niche conditions and support the growth of stem cells in vitro. However, current functional...

Adam D. Gracz, Ian A. Williamson, Kyle C. Roche, Michael J. Johnston… in Nature Cell Biology (2015)

Article

The angiogenic variation of skeletal site-specific human BMSCs from same alveolar cleft patients: a comparative study

Tissue engineering strategies hold great potential for alveolar cleft reconstruction. Bone marrow stromal cells (BMSCs) from iliac crest and craniofacial regions are candidate seeding cells with site-specific ...

Yifei Du, Fei Jiang, Yi Liang, Yuli Wang, Weina Zhou… in Journal of Molecular Histology (2016)

Article

Promotion of tumor-associated macrophages infiltration by elevated neddylation pathway via NF-κB-CCL2 signaling in lung cancer

Tumor-associated macrophages (TAMs) are the most abundant cancer stromal cells and play an essential role in tumor immunosuppression, providing a suitable microenvironment for cancer development and progressio...

Lisha Zhou, Yanyu Jiang, **aojun Liu, Lihui Li, Xuguang Yang, Changsheng Dong… in Oncogene (2019)