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  1. No Access

    Article

    Accuracy of skull strip** in a single-contrast convolutional neural network model using eight-contrast magnetic resonance images

    In automated analyses of brain morphometry, skull strip** or brain extraction is a critical first step because it provides accurate spatial registration and signal-intensity normalization. Therefore, it is i...

    Masami Goto, Yujiro Otsuka, Akifumi Hagiwara in Radiological Physics and Technology (2023)

  2. Article

    Open Access

    Use of a deep-learning-based lumen extraction method to detect significant stenosis on coronary computed tomography angiography in patients with severe coronary calcification

    Coronary computed tomography angiography examinations are increasingly becoming established as a minimally invasive method for diagnosing coronary diseases. However, although various imaging and processing met...

    Hidekazu Inage, Nobuo Tomizawa, Yujiro Otsuka in The Egyptian Heart Journal (2022)

  3. Article

    Open Access

    Convolutional neural network-based segmentation can help in assessing the substantia nigra in neuromelanin MRI

    This study aimed to evaluate the accuracy and diagnostic test performance of the U-net-based segmentation method in neuromelanin magnetic resonance imaging (NM-MRI) compared to the established manual segmentat...

    Alice Le Berre, Koji Kamagata, Yujiro Otsuka, Christina Andica in Neuroradiology (2019)

  4. Article

    Open Access

    Analysis of antihypertensive treatment using real-world Japanese data—the retrospective study of antihypertensives for lowering blood pressure (REAL) study

    Hypertension requires strict treatment because it causes diseases that can lead to death. Although various classes of antihypertensive drugs are available, the actual status of antihypertensive drug selection ...

    Mitsuru Ohishi, Takuo Yoshida, Akinori Oh, Shinzo Hiroi in Hypertension Research (2019)

  5. Article

    Open Access

    Analysis of second- and third-line antihypertensive treatments after initial therapy with an angiotensin II receptor blocker using real-world Japanese data

    Combination therapy using two or three classes of drugs is often required to treat hypertension to prevent cardiovascular disease. In this study, we examined combination therapies administered following initia...

    Shinzo Hiroi, Yukio Shimasaki, Takashi Kikuchi, Yujiro Otsuka in Hypertension Research (2016)