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  1. Article

    Open Access

    Cancer cell-specific and pro-apoptotic SMAC peptide-doxorubicin conjugated prodrug encapsulated aposomes for synergistic cancer immunotherapy

    Immunogenic cell death (ICD) is a crucial approach to turn immunosuppressive tumor microenvironment (ITM) into immune-responsive milieu and improve the response rate of immune checkpoint blockade (ICB) therapy...

    **seong Kim, Man Kyu Shim, Yujeong Moon, Jeongrae Kim… in Journal of Nanobiotechnology (2024)

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  2. Article

    Open Access

    Implantable micro-scale LED device guided photodynamic therapy to potentiate antitumor immunity with mild visible light

    Photodynamic therapy (PDT) is a promising strategy to promote antitumor immunity by inducing immunogenic cell death (ICD) in tumor cells. However, practical PDT uses an intense visible light owing to the shall...

    Jiwoong Choi, Il Seong Lee, Ju Seung Lee, Sangmin Jeon, Wan Su Yun… in Biomaterials Research (2022)

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  3. Article

    Open Access

    Preclinical development of carrier-free prodrug nanoparticles for enhanced antitumor therapeutic potential with less toxicity

    Nanomedicine has emerged as a promising strategy for cancer treatment. The most representative nanomedicine used in clinic is PEGylated liposomal doxorubicin DOXIL®, which is first FDA-approved nanomedicine. Howe...

    Man Kyu Shim, Suah Yang, Jooho Park, Jun Sik Yoon… in Journal of Nanobiotechnology (2022)

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