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Article
Efficacy of endoscopic surveillance for pharyngeal mucosa during endoscopic resection for pharyngeal carcinoma: a multicenter prospective study
Since patients with pharyngeal squamous cell carcinoma (SCC) often have multiple pharyngeal lesions, evaluation of pharyngeal lesions before endoscopic resection (ER) is important. However, detailed endoscopic...
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Article
Association between continuous cessation or reduction of drinking alcohol and improvement of multiple dysplastic lesions in patients with esophageal squamous cell carcinoma after endoscopic resection
Multiple development of squamous cell carcinoma (SCC) in the upper aerodigestive tract has been explained by the ‘field cancerization phenomenon’ associated with alcohol drinking. Squamous dysplastic lesion is...
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Article
Open AccessCorrection: Effect of food amount and temperature on growth rate and aerobic scope of juvenile chum salmon
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Article
Open AccessMYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis
Protein kinase A promotes beige adipogenesis downstream from β-adrenergic receptor signaling by phosphorylating proteins, including histone H3 lysine 9 (H3K9) demethylase JMJD1A. To ensure homeostasis, this pr...
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Article
Open AccessOptical biopsy for esophageal squamous cell neoplasia by using endocytoscopy
Endocytoscopy (ECS) enables microscopic observation in vivo for the gastrointestinal mucosa; however, there has been no prospective study in which the diagnostic accuracy of ECS for lesions that have not yet u...
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Article
Open AccessEffect of food amount and temperature on growth rate and aerobic scope of juvenile chum salmon
Offshore migration of Pacific salmon Oncorhynchus spp. is partly triggered by increasing body size and high motility in the early stages of life. The survival of juvenile salmon may depend on their growth rate du...
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Article
Open AccessGastric cancer complicated by paraneoplastic neurological syndrome which presented with extremity numbness: a case report
Paraneoplastic neurological syndromes refer to a group of neurological disorders, which occur as distant effects of malignant tumors and are not caused by metastasis, nutritional disorders, or side effects of ...
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Article
Open AccessPancreatic morphological abnormality that was challenging to differentiate from an ectopic pancreas: a case report
Protrusion of the lateral contour of the pancreatic head is a pancreatic morphological abnormality, which is known as rare shape atypia. We present a rare case of protrusion of the lateral contour of the pancr...
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Article
Open AccessEradication of Helicobacter pylori may improve dyspepsia in the elderly for the long term
Therapy for eradication of Helicobacter pylori (H. pylori) improves symptoms of H. pylori-associated dyspepsia (HPD), but the effects of eradication in elderly patients are unclear. The aim of our study was to in...
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Article
Experiment on endoscopic balloon dilation for esophageal stenosis after endoscopic submucosal dissection in pigs
Endoscopic balloon dilation (EBD) is effective for esophageal stenosis caused by ESD. However, an efficient EBD method has not been established. We, therefore, conducted EBD experiments on porcine esophageal s...
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Article
Histological and magnified endoscopic evaluation of villous atrophy in gastrointestinal graft-versus-host disease
Aim: To measure histological villous atrophy and to clarify the diagnostic accuracy of endoscopic villous atrophy in gastrointestinal graft-versus-host disease. Methods: Data for patients who underwent upper a...
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Article
Association between macrocytosis and metachronous squamous cell carcinoma of the esophagus after endoscopic resection in men with early esophageal squamous cell carcinoma
Macrocytosis is associated with an increased risk of squamous cell carcinoma (SCC) arising in the esophagus in men. The aim of this study was to evaluate the association between macrocytosis and metachronous S...
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Article
Open AccessDetection of early adenocarcinoma of the esophagogastric junction by spraying an enzyme-activatable fluorescent probe targeting Dipeptidyl peptidase-IV
It is still difficult to detect and diagnose early adenocarcinoma of the esophagogastric junction (EGJ) using conventional endoscopy or image-enhanced endoscopy. A glutamylprolyl hydroxymethyl rhodamine green ...
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Article
Open AccessClinical impact of the perioperative management of oral anticoagulants in bleeding after colonic endoscopic mucosal resection
Heparin bridging therapy (HBT) is indeed related to a high frequency of bleeding after endoscopic mucosal resection (EMR). In this study, our aim was to investigate clinical impact of management of oral antico...
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Article
Molecular identification of water molds (oomycetes) associated with chum salmon eggs from hatcheries in Japan and possible sources of their infection
Oomycete infection of various freshwater animals, including salmonid eggs, causes significant economic damage to aquaculture worldwide. In this study, we detected oomycetes in infected chum salmon Oncorhynchus ke...
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Article
Feasibility of a simplified narrow-band imaging classification system for Barrett’s esophagus for novice endoscopists
Narrow-band imaging (NBI) classifications for Barrett’s esophagus have been proposed for the detection of early esophageal adenocarcinoma. We developed a simplified classification system with demonstrated high...
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Article
Risk assessment of metachronous squamous cell carcinoma after endoscopic resection for esophageal carcinoma based on the genetic polymorphisms of alcoholdehydrogense-1B aldehyde dehydrogenase-2: temperance reduces the risk
Metachronous multiple squamous cell carcinoma (SCC) of the esophagus and the head and neck is commonly observed in patients who have previously undergone endoscopic resection (ER) for SCC of the esophagus (ESC...
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Article
Multicenter observational study on functional bowel disorders diagnosed using Rome III diagnostic criteria in Japan
The Rome III diagnostic criteria had been used to diagnose functional gastrointestinal disorders (FGIDs) world wide, and functional bowel disorders (FBDs) including irritable bowel syndrome (IBS) have recently...
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Article
Cecum ulcer is a reliable endoscopic finding in cytomegalovirus colitis concomitant with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Although graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), cytomegalovirus (CMV) reactivation also occurs in patients after allo-HSCT...
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Article
Endoscopic ultrasonography features of gastric mucosal cobblestone-like changes from a proton-pump inhibitor
A 68-year-old man with no symptoms presented to Hokkaido University Hospital for esophagogastroduodenoscopy screening. He had a history of Helicobacter pylori eradication. Initial esophagogastroduodenoscopy showe...
