Skip to main content

6 Result(s)

within YueQuan Shen Remove this filter Life Sciences, general Remove this filter

and

  1. Article

    Open Access

    Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway

    The tumor suppressor Merlin/NF2 functions upstream of the core Hippo pathway kinases Lats1/2 and Mst1/2, as well as the nuclear E3 ubiquitin ligase CRL4DCAF1. Numerous mutations of Merlin have been identified in ...

    Youjun Li, Hao Zhou, Fengzhi Li, Siew Wee Chan, Zhijie Lin, Zhiyi Wei… in Cell Research (2015)

    Download PDF (5010 KB) View Article

  2. No Access

    Article

    Molecular mechanism of mitochondrial calcium uptake

    Mitochondrial calcium uptake plays a critical role in various cellular functions. After half a century of extensive studies, the molecular components and important regulators of the mitochondrial calcium uptak...

    Lele Wang, Xue Yang, Yuequan Shen in Cellular and Molecular Life Sciences (2015)

  3. Article

    Open Access

    Structure of the kinase domain of human RNA-dependent protein kinase with K296R mutation reveals a face-to-face dimer

    RNA-dependent protein kinase (PKR) is crucial for the innate immune response, cell growth, proliferation, signal transduction and apoptosis. The activation process of PKR has been studied for many years and is...

    FengZhi Li, SiWei Li, Zheng Wang, YueQuan Shen, TongCun Zhang… in Chinese Science Bulletin (2013)

    Download PDF (811 KB)

  4. No Access

    Article

    Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2

    Protein kinase CK2 consists of two catalytic subunits (CK2α) and two regulatory subunits (CK2β). Here, we report the crystal structures of rat CK2α mutant (rCK2α-ΔC, 1–335) and CK2β (rCK2β). The overall topolo...

    WeiHong Zhou, **aoHong Qin, **aoJie Yan, **ngQiao **e, Liang Li… in Chinese Science Bulletin (2009)

  5. No Access

    Article

    Crystallographic studies on the binding of coenzyme analogs to D-glyceraldehyde-3-phosphate dehydrogenase fromPalinurus versicolor

    In contrast with the coezyme, two coenzyme analogs, ADP-ribose and SNAD, bind non-cooperatively to D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH).Palinurus versicolor (PV) GAPDH complexed with ADP-ribose and ...

    Yuequan Shen, Zhaojie Wang, Shiying Song, Junmei Zhou… in Chinese Science Bulletin (2000)

  6. No Access

    Article

    Structure of D-glyceraldehyde-3-phosphate dehydrogenase fromPalinurus versicolor in a tetragonal crystal form

    D-glyceraldehyde-3-phosphate dehydrogenase (holo-GAPDH) fromPalinurus versicolor was crystallized in a novel crystal form by the method of sitting-drop vapor diffusion. The crystals have space groupP4212, cell pa...

    Yuequan Shen, Shiying Song, Zhengjiong Lin in Science in China Series C: Life Sciences (2000)