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Article
Fascia patchwork closure for endoscopic endonasal skull base surgery
With the development of endoscopic technology and surgery, resection of midline skull base tumors has been achieved using endoscopic endonasal skull base (EESB) approaches. EESB approaches reportedly have a gr...
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Protocol
Quantum Dot-Based In Situ Hybridization and Immunohistochemistry to Detect mRNA and Protein at Subcellular Levels, Comparison with Studies Using Electron Microscopy
Semiconductor nanocrystals (Quantum dots, Qdots) have advantages of narrow, symmetric emission spectra with multiple resolvable colors that can be excited simultaneously using a single excitation wavelength. T...
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Article
A simple, safe, and effective method of cyst wall removal for Rathke’s cleft cyst
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Article
Endocan, a new invasion and angiogenesis marker of pituitary adenomas
Angiogenesis plays a crucial role in tumor growth. Recently, endocan has emerged as a new marker of vascular endothelial cells from cancers in other organs. In this study, we elucidated the relationship betwee...
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Article
Molecular status of pituitary carcinoma and atypical adenoma that contributes the effectiveness of temozolomide
There have been several reports of temozolomide (TMZ) treatment of pituitary carcinomas and atypical adenomas. O6-methyl-guanine-DNA methyltransferase is not the sole molecule determining the sensitivity to TMZ i...
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Article
Open AccessSkull base osteosarcoma presenting with cerebrospinal fluid leakage after CyberKnife® treatment: a case report
CyberKnife® radiation is an effective treatment for unresectable skull base tumors because it can deliver a highly conformational dose distribution to the complex shapes of tumor extensions. There have been few r...
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Article
Open AccessAdvanced therapeutic strategy for radiation-induced osteosarcoma in the skull base: a case report and review
A review of patients with skull base osteosarcoma secondary to radiation (radiation-induced osteosarcoma: RIOS) of the pituitary tumor shows the mean survival of approximately 7 months (2 weeks – 16 months). T...
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Article
Easy slip-knot: a new simple tying technique for deep sutures
Knot-tying in the deep operative field is very complicated because of the narrow working space during endoscopic transsphenoidal surgery. We present a novel technique for tying deep knots called the “easy slip...
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Article
Immunohistochemical Detection of Somatostatin Receptor (SSTR) Subtypes 2A and 5 in Pituitary Adenoma from Acromegalic Patients: Good Correlation with Preoperative Response to Octreotide
The aim of this study was to determine the correlation between the expression of somatostatin receptors by immunohistochemistry and the percent suppression of GH levels in the octreotide suppression test.