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  1. No Access

    Article

    Curcumin Ameliorates Memory Decline via Inhibiting BACE1 Expression and β-Amyloid Pathology in 5×FAD Transgenic Mice

    Alzheimer’s disease (AD) is the most common dementia and the trigger of its pathological cascade is widely believed to be the overproduction and accumulation of β-amyloid protein (Aβ) in the affected brain. Ho...

    Kunmu Zheng, **aoman Dai, Nai’an **ao, **lin Wu, Zhen Wei… in Molecular Neurobiology (2017)

  2. No Access

    Article

    Heart failure research in China: current status and future direction

    Heart failure is a major public health problem worldwide. Despite advances in the therapy and care of heart failure, morbidity and mortality remain persistently high. Recent years have witnessed major breakth...

    Yuangui Zhu, Ruijuan Sun, Erdan Dong in Science Bulletin (2016)

  3. Article

    Open Access

    Astaxanthin protects against MPP+-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis

    Although the etiology of PD remains unclear, increasing evidence has shown that oxidative stress plays an important role in its pathogenesis and that of other neurodegenerative disorders. NOX2, a cytochrome su...

    Qinyong Ye, Bixia Huang, **aodong Zhang, Yuangui Zhu, **aochun Chen in BMC Neuroscience (2012)

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  4. Article

    Open Access

    Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway

    Parkinson’s disease is a high incidence neurodegenerative disease in elderly people, and oxidative stress plays an important role in the pathogenesis. Oxygen metabolism in the brain is high, which lacks an ant...

    Qinyong Ye, Linfeng Ye, **anjie Xu… in BMC Complementary and Alternative Medicine (2012)

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