8 Result(s)
within
English
Animal Genetics and Genomics
Life Sciences, general
YuanYuan Li
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Article
Open AccessGenome-wide identification and characterization of the bHLH gene family and analysis of their potential relevance to chlorophyll metabolism in Raphanus sativus L
Green-fleshed radish (Raphanus sativus L.) is an economically important root vegetable of the Brassicaceae family, and chlorophyll accumulates in its root tissues. It was reported that the basic helix-loop-helix ...
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Article
Open AccessPredicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines
Human cancer cell line profiling and drug sensitivity studies provide valuable information about the therapeutic potential of drugs and their possible mechanisms of action. The goal of those studies is to tran...
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Article
Open AccessHigh-density genetic linkage map construction and cane cold hardiness QTL map** for Vitis based on restriction site-associated DNA sequencing
Cold hardiness is an important agronomic trait and can significantly affect grape production and quality. Until now, there are no reports focusing on cold hardiness quantitative trait loci (QTL) map**. In th...
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Article
Open AccessPutative biomarkers for predicting tumor sample purity based on gene expression data
Tumor purity is the percent of cancer cells present in a sample of tumor tissue. The non-cancerous cells (immune cells, fibroblasts, etc.) have an important role in tumor biology. The ability to determine tumo...
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Article
Open AccessA comprehensive genomic pan-cancer classification using The Cancer Genome Atlas gene expression data
The Cancer Genome Atlas (TCGA) has generated comprehensive molecular profiles. We aim to identify a set of genes whose expression patterns can distinguish diverse tumor types. Those features may serve as bioma...
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Article
Open AccessT-KDE: a method for genome-wide identification of constitutive protein binding sites from multiple ChIP-seq data sets
A protein may bind to its target DNA sites constitutively, i.e., regardless of cell type. Intuitively, constitutive binding sites should be biologically functional. A prerequisite for understanding their funct...
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Article
Open AccessCharacterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes
Recent studies suggested that human/mammalian genomes are divided into large, discrete domains that are units of chromosome organization. CTCF, a CCCTC binding factor, has a diverse role in genome regulation i...
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Article
Open AccessExploring photosynthesis evolution by comparative analysis of metabolic networks between chloroplasts and photosynthetic bacteria
Chloroplasts descended from cyanobacteria and have a drastically reduced genome following an endosymbiotic event. Many genes of the ancestral cyanobacterial genome have been transferred to the plant nuclear ge...
