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Article
Open AccessASS1 inhibits triple-negative breast cancer by regulating PHGDH stability and de novo serine synthesis
Argininosuccinate synthase (ASS1), a critical enzyme in the urea cycle, acts as a tumor suppressor in many cancers. To date, the anticancer mechanism of ASS1 has not been fully elucidated. Here, we found that ...
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Article
Flexible, recyclable, shape memory biomass supramolecular composite films from castor oil and ethyl cellulose
To improve the flexibility, functionality and recyclability of ethyl cellulose (EC)-based film materials, firstly methyl-nadic-anhydride-modified ethyl cellulose (NEC) was synthesized from EC, and then epoxy c...
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Article
Open AccessCXCL10 is a prognostic marker for pancreatic adenocarcinoma and tumor microenvironment remodeling
The tumor microenvironment (TME) plays a crucial role in the progression of pancreatic adenocarcinoma (PAAD). However, challenges remain regarding the role played by TME associated genes in the prognosis of PAAD.
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Article
A scoring model predicting overall survival for hepatocellular carcinoma patients who receive surgery and chemotherapy
Surgery is the most effective way to cure hepatocellular carcinoma, and chemotherapy is the basic adjuvant treatment. For hepatocellular carcinoma patients who receive surgery and chemotherapy, survival progno...
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Article
Open AccessA new finding in the key prognosis-related proto-oncogene FYN in hepatocellular carcinoma based on the WGCNA hub-gene screening trategy
Hepatocellular carcinoma (HCC) is the third-most deadly cancer worldwide. More breakthroughs are needed in the clinical practice for liver cancer are needed, and new treatment strategies are required. This stu...
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Article
Open AccessShort-term effects of two types of goggles on intraocular pressure and anterior eye segment biometrics
To evaluate and compare the changes in intraocular pressure and anterior eye segment biometrics during and after wearing two types of commonly used swimming goggles.
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Article
A novel one-step quantitative reverse transcription PCR assay for selective amplification of hepatitis B virus pregenomic RNA from a mixture of HBV DNA and RNA in serum
Current antiviral therapies against hepatitis B virus (HBV) infections, such as treatment with nucleos(t)ide analogs (NAs) and interferon alpha, can significantly lower HBV DNA titers, eventually to undetectab...
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Article
Open AccessUltrafast Synthesis of Multifunctional Submicrometer Hollow Silica Spheres in Microfluidic Spiral Channels
We demonstrate a facile and ultrafast approach for the synthesis of multifunctional submicrometer hollow silica spheres (smHSSs) using microfluidic spiral channels with enhanced mixing performance, introduced ...
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Article
Investigation and improvement of reversible microfluidic devices based on glass–PDMS–glass sandwich configuration
Reversibly assembled microfluidic devices are dismountable and reusable, which is useful for a number of applications such as micro- and nano-device fabrication, surface functionalization, complex cell pattern...
