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Article
Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition
The female gamete (the oocyte) serves the distinct purpose of transmitting the maternal genome and other maternal factors that are critical for post-ovulation events1,2,3,4. Through the identification and charact...
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Article
Synthesis, crystal structures, and DNA-binding properties of zinc(II) and nickel(II) complexes with tris[2-(N-ethyl)benzimidazylmethyl]amine and cinnamate ligands
Tris[2-(N-ethyl)benzimidazylmethyl]amine (Etntb) and two of its complexes, [Zn(Etntb)(cinnamate)]NO3·2DMF (1) and [Ni(Etntb)(cinnamate)·(H2O)]NO3 (2) have been synthesized and characterized by phy...
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Article
Synthesis, crystal structures, antioxidant activities and DNA-binding studies of two manganese(II) complexes with 1,3-bis(1-ethylbenzimidazol-2-yl)-2-oxopropane ligands
Two manganese(II) complexes, [Mn(Etobb)2](pic)2·2DMF (pic = picrate) 1 and Mn(Etobb)Cl2 2, where Etobb is 1,3-bis(1-ethylbenzimidazol-2-yl)-2-oxopropane, were synthesized and characterized by phys...
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Article
Synthesis, structure, antioxidation, and DNA-binding studies of a binuclear ytterbium(III) complex with bis(N-salicylidene)-3-oxapentane-1,5-diamine
A new complex of ytterbium(III) nitrate with bis(N-salicylidene)-3-oxapentane-1,5-diamine (H2L), with the composition Yb2(L)2(NO3)2·2H2O, was synthesized and characterized by physic-chemical and spectroscopic met...
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Article
Open AccessThe prognostic significance of Cdc6 and Cdt1 in breast cancer
DNA replication is a critical step in cell proliferation. Overexpression of MCM2-7 genes correlated with poor prognosis in breast cancer patients. However, the roles of Cdc6 and Cdt1, which work with MCMs to r...
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Article
Open AccessComprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS)...
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Article
Open AccessRNA sequencing analysis reveals quiescent microglia isolation methods from postnatal mouse brains and limitations of BV2 cells
Microglia play key roles in neuron–glia interaction, neuroinflammation, neural repair, and neurotoxicity. Currently, various microglial in vitro models including primary microglia derived from distinct isolati...
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Article
Effects of sputtering power of SnO2 electron selective layer on perovskite solar cells
Efficient perovskite solar cell (PSC) with SnO2 electron selective layer (ESL) prepared by radio frequency magnetron sputtering method at room-temperature has been realized. In this work, we systematically discus...
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Article
Open AccessA comparison of different oxidative pretreatments on polysaccharide hydrolyzability and cell wall structure for interpreting the greatly improved enzymatic digestibility of sugarcane bagasse by delignification
In order to confirm the contribution of delignification to the increase in lignocellulosic cellulose digestibility, several laboratory oxidative pretreatments under mild conditions, including alkaline-hydrogen...
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Article
Optimal impulsive time-fixed transfers around the libration points of the restricted three-body problem
A methodology is proposed to design optimal time-fixed impulsive transfers in the vicinity of the L2 libration point of the Earth-Moon system, taking the construction of a space station around the collinear li...
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Article
Open AccessA primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats
Antibody phage display is a powerful platform for discovery of clinically applicable high affinity monoclonal antibodies against a broad range of targets. Libraries generated from immunized animals offer the a...
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Article
Open AccessReconstruction of full-length ureter defects by laparoscopic bladder flap forming
To evaluate the safety and efficacy of laparoscopic bladder muscle flap reconstruction in the treatment of extensive ureteral avulsion. Patients with full-length (re length > 20 cm) and upper ureteral (avulsi...
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Article
Conversion of Glucose to 5-Hydroxymethylfurfural by Co-catalysis of p-Toluenesulfonic Acid (pTSA) and Chlorides: A Comparison Based on Kinetic Modeling
Hydroxymethylfurfural (HMF) has been considered as one of the most promising biomass derived precursors for producing bio-based materials. Lewis acids are usually used to facilitate the isomerization of glucos...
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Article
Open AccessBioinformatics analysis of C3 and CXCR4 demonstrates their potential as prognostic biomarkers in clear cell renal cell carcinoma (ccRCC)
The molecular prognostic biomarkers of clear cell renal cell carcinoma (ccRCC) are still unknown. We aimed at researching the candidate biomarkers and potential therapeutic targets of ccRCC.
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Article
Production of highly sensitive monoclonal antibody and development of lateral flow assays for phallotoxin detection in urine
Phallotoxins, toxic cyclopeptides found in wild poisonous mushrooms, are predominant causes of fatal food poisoning. For the early and rapid diagnosis mushroom toxin poisoning, a highly sensitive and robust mo...
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Article
Open AccessClinical outcome of laparoscopic versus robot-assisted radical cystectomy for patients with bladder cancer: a retrospective study
With the development of minimally invasive surgery technology, patients with bladder cancer are increasingly receiving laparoscopic radical cystectomy (LRC) or robotic-assisted radical cystectomy (RARC) treatm...
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Article
Anisotropic Optoelectronic Properties of MAPbI3 on (100), (112) and (001) Facets
Large-size single crystals of MAPbI3 were grown using inverse temperature crystallization. The crystalline anisotropy is important for understanding, designing and controlling the growth and properties of MAPbI3 ...
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Functional Recovery POST-RALP: Continence
Preservation of postoperative urinary continence remains the primary concern of males and their surgeons following robot-assisted radical prostatectomy (RARP). Without doubt, continence was the most important ...
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Article
Correction to: Anisotropic Optoelectronic Properties of MAPbI3 on (100), (112) and (001) Facets
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Article
Open AccessYBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells
In heterogeneous head and neck cancer (HNC), subtype-specific treatment regimens are currently missing. An integrated analysis of patient HNC subtypes using single-cell sequencing and proteome profiles reveals...
