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Article
Open AccessExploring ALK fusion in colorectal cancer: a case series and comprehensive analysis
Anaplastic lymphoma kinase (ALK) fusion-positive colorectal cancer (CRC) is a rare and chemotherapy-refractory subtype that lacks established and effective treatment strategies. Additionally, the efficacy and ...
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Article
Usability evaluation of monocular optical head-mounted displays on reading tasks
This study explores the factors affecting reading time, error rate, visual fatigue, and mental workload of subjects using a monocular optical head-mounted display (OHMD). Forty healthy participants were involv...
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Article
Application of the metal ions as potential population biomarkers for wastewater-based epidemiology: estimating tobacco consumption in Southern China
Wastewater-based epidemiology (WBE) is an objective approach for the estimation of population-level exposure to a wide range of substances, in which the use of a population biomarker (PB) could significantly r...
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Article
Inverse analysis of the residual stress in laser-assisted milling
In laser-assisted milling, higher temperature in shear zone softens the material potentially resulting in a shift of mean residual stress, which significantly affects the damage tolerance and fatigue performan...
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Article
Residual stress prediction in ultrasonic vibration–assisted milling
In the current study, an analytical predictive model on residual stress after ultrasonic vibration–assisted milling is proposed in an effort to provide an accurate and reliable reference. Three types of tool-w...
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Article
Inverse analysis of the tool life in laser-assisted milling
In current study, an inverse analysis is conducted on tool life based on five process parameters, by predicting tool life based on guessed process parameters, which is defined as the forward problem, and apply...
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Article
Sulfuretin protects hepatic cells through regulation of ROS levels and autophagic flux
Palmitate (PA) exposure induces stress conditions featuring ROS accumulation and upregulation of p62 expression, resulting in autophagic flux blockage and cell apoptosis. Sulfuretin (Sul) is a natural product ...
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Article
Pathology Evaluation of Reduction Mammaplasty Specimens and Subsequent Diagnosis of Malignant Breast Disease: A Claims-Based Analysis
This study aimed to measure the use of pathology evaluation of breast specimens among patients undergoing reduction mammaplasty and assess rates of new diagnoses of breast disease and associated cost.
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Article
Chemical cocktails enable hepatic reprogramming of human urine-derived cells with a single transcription factor
Human liver or hepatocyte transplantation is limited by a severe shortage of donor organs. Direct reprogramming of other adult cells into hepatic cells may offer a solution to this problem. In a previous study...
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Article
Residual stress prediction in laser-assisted milling considering recrystallization effects
An analytical predictive model for residual stress in laser-assisted milling considering material recrystallization caused by laser preheating is proposed. The laser preheating temperature field is predicted b...
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Article
Analytical prediction of temperature in laser-assisted milling with laser preheating and machining effects
An analytical predictive model for temperature in laser-assisted milling considering both laser preheating temperature and machining induced temperature rise is proposed. The preheating temperature at top surf...
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Article
Inverse Analysis of Inconel 718 Laser-Assisted Milling to Achieve Machined Surface Roughness
This manuscript proposes an inverse analysis method for the machined surface roughness in laser-assisted milling on Inconel 718. The method solves the forward problem considering the tool profile and the elast...
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Article
A New Phloroglucinol Derivative from Syzygium austroyunnanense
A new phloroglucinol derivative, 1-(2,4-dihydroxy-6-methoxyphenyl)-1-tridecanone (1), along with a known analogue, 1-(2,4,6-trihydroxyphenyl)-1-hexadecanone (2), was isolated from the leaves of Syzygium austroyun...
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Article
Inverse analysis of the cutting force in laser-assisted milling on Inconel 718
Inverse analysis is of value identifying viable solutions of process parameters that can achieve specified process performance. In this study, an inverse analysis method is proposed for the cutting force in la...
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Article
Force modeling of Inconel 718 laser-assisted end milling under recrystallization effects
Recrystallization effects are considered for the proposed force modeling method of Inconel 718 laser-assisted end milling. Oblique cutting forces are transferred to equivalent orthogonal cutting forces through...
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Article
Analytical model for force prediction in laser-assisted milling of IN718
Laser-assisted machining (LAM) could help to significantly reduce the machining forces and improve machinability of hard to machine materials. The physical ground explanation for machinability improvement of t...
