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Article
β-arrestin2 deficiency ameliorates S-100-induced autoimmune hepatitis in mice by inhibiting infiltration of monocyte-derived macrophage and attenuating hepatocyte apoptosis
Autoimmune hepatitis (AIH) is a progressive hepatitis syndrome characterized by high transaminase levels, interface hepatitis, hypergammaglobulinemia, and the presence of autoantibodies. Misdiagnosis or delaye...
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Article
Open AccessEffects of Mindfulness-Based Elder Care (MBEC) on symptoms of depression and anxiety and spiritual well-being of institutionalized seniors with disabilities: a randomized controlled trial
Despite the need to incorporate seniors from various settings into mindfulness-based empirical research, issues of geriatric frailties and non-compliance remain. This study aimed to evaluate the effects of a m...
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Article
Yinlai Decoction Protects Microstructure of Colon and Regulates Serum Level of D-Lactic Acid in Pneumonia Mice Fed with High-Calorie and High-Protein Diet
To investigate the effect of Yinlai Decoction (YD) on the microstructure of colon, and activity of D-lactic acid (DLA) and diamine oxidase (DAO) in serum of pneumonia mice model fed with high-calorie and high-...
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Article
Mn3O4@polyaniline nanocomposite with multiple active sites to capture uranium(VI) and iodide: synthesis, performance, and mechanism
A major challenge for radioactive wastewater treatment and associated environmental remediation is how to simultaneously remove cationic and anionic radionuclides. Herein, a series of Mn3O4@polyaniline (Mn3O4@PAN...
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Article
Open AccessAdipocyte-derived kynurenine promotes obesity and insulin resistance by activating the AhR/STAT3/IL-6 signaling
Aberrant amino acid metabolism is a common event in obesity. Particularly, subjects with obesity are characterized by the excessive plasma kynurenine (Kyn). However, the primary source of Kyn and its impact on...
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Article
Open AccessMelatonin abolished proinflammatory factor expression and antagonized osteoarthritis progression in vivo
Progressive structural changes in osteoarthritis (OA) involve synovial inflammation and angiogenesis, as well as activation of the proinflammatory cytokines tumor necrosis factor alpha (TNF-α) and interleukin ...
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Article
Open AccessHuman ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
Human ribonuclease 1 (hRNase 1) is critical to extracellular RNA clearance and innate immunity to achieve homeostasis and host defense; however, whether it plays a role in cancer remains elusive. Here, we demo...
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Article
Open AccessA modified cardiac triage strategy reduces door to ECG time in patients with ST elevation myocardial infarction
Timely performing electrocardiography (ECG) is crucial for early detection of ST-elevation myocardial infarction (STEMI). For shortening door-to-ECG time, a chief complaint-based “cardiac triage” protocol comp...
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Article
Open AccessGalectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy
The two T cell inhibitory receptors PD-1 and TIM-3 are co-expressed during exhausted T cell differentiation, and recent evidence suggests that their crosstalk regulates T cell exhaustion and immunotherapy effi...
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Article
Open AccessRNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination
Patients with lung adenocarcinoma (LUAD) have high mortality rate and poor prognosis. The LUAD cells display increased aerobic glycolysis, which generates energy required for their survival and proliferation. ...
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Chapter and Conference Paper
An Image Acquisition and Processing Technique Based on Machine Vision
This paper takes the two-dimensional code image recognition technology as an example to introduce the image acquisition and processing technology based on machine vision. Our object is to filter noise reductio...
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Chapter and Conference Paper
Analysis of Influence of Antenna Azimuth on the Performance in a MIMO System
As a typical technique of the fourth and fifth generation mobile communication, Multiple-Input and Multiple-Output (MIMO) technology can achieve the optimal channel capacity by configuring the antenna azimuth,...
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Chapter and Conference Paper
Modeling of Maritime Wireless Communication Channel
Influenced by radian of the Earth and the waves, also the shelter of ships and sea waves, wireless channels above the sea have the effects of deep fading and multipath. Microwaves of very high frequency and ul...
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Chapter
Contemporary Themes in the Design of AT for the Ageing Population: Materiality, Co-design and Cultural Influences
Products we purchase are much more than artefacts that fulfil functional needs in our life. We have grown to enact our consumer choices, even those regarding fast moving consumable goods, with careful consider...
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Article
Deubiquitinase Mysm1 regulates macrophage survival and polarization
Macrophages play pivotal roles in innate and adaptive immune response, tissue homeostasis and cancer development. Their development and heterogeneity are tightly controlled by epigenetic program and transcript...
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Article
Down-regulation of Noggin and miR-138 coordinately promote osteogenesis of mesenchymal stem cells
Mesenchymal stem cells (MSCs) can differentiate to osteocytes under suitable conditions. In recent years, micro-nucleotides have been progressively used to modulate gene expression in cells due to the consider...
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Article
In vitro functional characterization of 37 CYP2C9 allelic isoforms found in Chinese Han population
Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme that is responsible for the metabolism of approximately 15% of clinically important drugs. The aim of this study was to assess the catalytic characteristics...
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Article
The relationship between bank performance and intellectual capital in East Asia
In this paper, we develop a performance efficiency value by using data envelopment analysis (DEA) to integrate five perspectives of CAMEL (Capital Adequacy, Asset Quality, Management, Earnings, Liquidity), whi...
