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Article
Open AccessThe changes of neuroactivity of Tui Na (Chinese massage) at Hegu acupoint on sensorimotor cortex in stroke patients with upper limb motor dysfunction: a fNIRS study
Tui Na (Chinese massage) is a relatively simple, inexpensive, and non-invasive intervention, and has been used to treat stroke patients for many years in China. Tui Na acts on specific parts of the body which ...
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Article
Enhanced oxidation resistance of low-carbon MgO–C refractories with ternary carbides: a review
The demand for low-carbon MgO–C refractories is ever growing to meet the development of advanced steelmaking technologies and efficient energy conservation. Meanwhile, to improve the oxidation resistance and i...
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Article
Open AccessColorectal cancer-associated fibroblasts promote metastasis by up-regulating LRG1 through stromal IL-6/STAT3 signaling
Cancer-associated fibroblasts (CAFs) have been shown to play a strong role in colorectal cancer metastasis, yet the underlying mechanism remains to be fully elucidated. Using CRC clinical samples together with...
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Article
Open AccessCancer-associated fibroblasts impact the clinical outcome and treatment response in colorectal cancer via immune system modulation: a comprehensive genome-wide analysis
Cancer-associated fibroblasts (CAFs) in the tumour microenvironment are associated with poor prognosis and chemoresistance in multiple solid tumours. However, there is a lack of universal measures of CAFs in c...
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Article
Open AccessStromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
BRD4, a Bromodomain and Extraterminal (BET) protein family member, is a promising anti-cancer drug target. However, resistance to BET inhibitors targeting BRD4 is common in solid tumors. Here, we show that can...
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Article
Open AccessTreatment of posterolateral tibial plateau fractures with a rotational support plate and special pressurizer: technical note and retrospective case series
In tibial plateau fractures, the posterolateral segment of the tibia plateau is frequently affected and challenging to treat. Although there are many surgical approaches and fixation methods for the treatment ...
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Article
Open AccessCorrection to: Protein–protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessProtein–protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer
Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with stem cell property. Increased evidence suggest that CSCs could be responsible for chemoresistance and recurrence in colorectal can...
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Article
Optimizing mandibular sagittal split of large maxillomandibular advancements for obstructive sleep apnea: patient and surgical factors
Maxillomandibular advancement (MMA) confers consistent and high rates of surgical success for obstructive sleep apnea (OSA). In the era of value-based medicine, identifying factors that affect the stability of...
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Article
Traffic flow guidance algorithm in intelligent transportation systems considering the effect of non-floating vehicle
Based on the hypothesis that all vehicles on roads are floating vehicles equipped with vehicular terminals and upload their traffic information to the traffic control center in real time, many traffic flow gui...
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Article
An improved two-lane cellular automaton traffic model based on BL-STCA model considering the dynamic lane-changing probability
Based on the brake light (BL) model, Knospe et al. proposed a symmetric two-lane cellular automaton (BL-STCA) model, which could reproduce various empirically observed two-lane phenomena. In real traffic, the ...
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Article
Open AccessA signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients
The hypoxic tumor microenvironment accelerates the invasion and migration of colorectal cancer (CRC) cells. The aim of this study was to develop and validate a hypoxia gene signature for predicting the outcome...
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Article
Open AccessInvolvement of abscisic acid-responsive element-binding factors in cassava (Manihot esculenta) dehydration stress response
Cassava (Manihot esculenta) is a major staple food, animal feed and energy crop in the tropics and subtropics. It is one of the most drought-tolerant crops, however, the mechanisms of cassava drought tolerance re...
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Article
LC-MS/MS Identification of Novel Saponins from the Viscera of Sea Cucumber Apostichopus japonicus
Sea cucumbers, soft-bodied wormlike echinoderms, are traditionally consumed in China. Sea cucumber viscera are often discarded during production. In this study, we characterized saponins present in the viscera...
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Article
17β-Estradiol and/or estrogen receptor alpha blocks isoproterenol-induced calcium accumulation and hypertrophy via GSK3β/PP2A/NFAT3/ANP pathway
The present study was aimed to investigate the protective effects of 17β-estradiol (E2) and estrogen receptor α (ERα) on isoproterenol (ISO)-treated H9c2 cardiomyoblast cells. In the present study, we treated ...
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Article
Open AccessHypoglossal nerve stimulation for treatment of obstructive sleep apnea (OSA): a primer for oral and maxillofacial surgeons
The prevalence of obstructive sleep apnea (OSA) is estimated to be 1–5% of the adult population world-wide, and in Korea, it is reported at 4.5% of men and 3.2% of women (Age 40 to 69 years old). Active treatm...
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Article
Noninvasive Detection and Imaging of Matrix Metalloproteinases for Cancer Diagnosis
Matrix metalloproteinases (MMPs) are important cancer biomarkers and the sensitive detection of MMPs is of great importance to improve clinical diagnosis and therapy of cancer at its early stage. Molecular ima...
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Chapter and Conference Paper
Investigation on the Characteristics of DC Air Discharge at Low Pressure Based on Hydrodynamics and Chemistry Model
Firstly, a presented model of hydrodynamics and chemistry which introduces an improved nonlocal collisionless electron heat flux and photoionization effect is used to simulate the low-pressure air discharge of...
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Article
Study and Application of Camber Control Model of Intermediate Slab in Rough Rolling
In order to solve the camber problem of intermediate slab in a domestic conventional hot rolling mill, a three-dimensional elastic-plastic dynamic model was built through finite element method to quantitativel...
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Article
Extracellular Signal-Regulated Kinase 5 in the Cerebrospinal Fluid-Contacting Nucleus Contributes to Morphine Physical Dependence in Rats
The cerebrospinal fluid-contacting nucleus (CSF-CN) may influence actual composition of the CSF for non-synaptic signal transmission via releasing or absorbing bioactive substances, which distributes and local...
