2 Result(s)

Article

Development of a novel individualized warfarin dose algorithm based on a population pharmacokinetic model with improved prediction accuracy for Chinese patients after heart valve replacement

The gene-guided dosing strategy of warfarin generally leads to over-dose in patients at doses lower than 2 mg/kg, and only 50% of individual variability in daily stable doses can be explained. In this study, w...

Yu-bin Zhu, **an-hua Hong, Meng Wei, **g Hu, **n Chen… in Acta Pharmacologica Sinica (2017)