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  1. Article

    Open Access

    Clinical significance and prospective mechanism of increased CDKN2A expression in small cell lung cancer

    Although it has been shown that cyclin dependent kinase inhibitor 2A (CDKN2A) plays a significant role in a number of malignancies, its clinicopathological value and function in small cell lung cancer (SCLC) i...

    Dong-Ming Li, Guo-Sheng Li, Jian-Di Li, Feng Chen in Clinical and Translational Oncology (2024)

  2. No Access

    Article

    CDK6 is a novel predictive and prognosis biomarker correlated with immune infiltrates in multiple human neoplasms, including small cell lung carcinoma

    The roles of cyclin-dependent kinase 6 (CDK6) in various cancers, including small cell lung carcinoma (SCLC), remain unclear. Here, 111,54 multi-center samples were investigated to determine the expression, clini...

    Guo-Sheng Li, Zhi-Guang Huang, Dong-Ming Li in Functional & Integrative Genomics (2023)

  3. No Access

    Article

    ITGB4 Serves as an Identification and Prognosis Marker Associated with Immune Infiltration in Small Cell Lung Carcinoma

    Integrin beta 4 (ITGB4) is a vital factor for numerous cancers. However, no reports regarding ITGB4 in small cell lung carcinoma (SCLC) have been found in the existing literature. This study systematically invest...

    Guo-Sheng Li, Zhi-Guang Huang, Rong-Quan He, Wei Zhang in Molecular Biotechnology (2023)

  4. Article

    Open Access

    Identification through machine learning of potential immune- related gene biomarkers associated with immune cell infiltration in myocardial infarction

    To investigate the potential role of immune-related genes (IRGs) and immune cells in myocardial infarction (MI) and establish a nomogram model for diagnosing myocardial infarction.

    Hao Dong, Shi-Bai Yan, Guo-Sheng Li, Zhi-Guang Huang in BMC Cardiovascular Disorders (2023)

  5. Article

    Open Access

    Downregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining

    The molecular mechanism of laryngeal squamous cell carcinoma (LSCC) is not completely clear, which leads to poor prognosis and treatment difficulties for LSCC patients. To date, no study has reported the exact...

    Fang-Cheng Jiang, Jia-Yuan Luo, Yi-Wu Dang in World Journal of Surgical Oncology (2022)

  6. Article

    Open Access

    The clinical significance of integrin subunit alpha V in cancers: from small cell lung carcinoma to pan-cancer

    Little is known about the relationship between integrin subunit alpha V (ITGAV) and cancers, including small cell lung cancer (SCLC).

    Yu-Lu Tang, Guo-Sheng Li, Dong-Ming Li, Deng Tang in BMC Pulmonary Medicine (2022)

  7. Article

    Open Access

    Clinical assessment and molecular mechanism of the upregulation of Toll-like receptor 2 (TLR2) in myocardial infarction

    The prevalence and mortality of cardiovascular diseases remain ranked first worldwide. Myocardial infarction (MI) is the central cause of death from cardiovascular diseases, seriously endangering human health....

    Ming-Jie Li, Shi-Bai Yan, Hao Dong, Zhi-Guang Huang in BMC Cardiovascular Disorders (2022)