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    Article

    The Structure and Function of Glial Networks: Beyond the Neuronal Connections

    Glial cells, consisting of astrocytes, oligodendrocyte lineage cells, and microglia, account for >50% of the total number of cells in the mammalian brain. They play key roles in the modulation of various brain...

    Hai-Rong Peng, Yu-Kai Zhang, Jia-Wei Zhou in Neuroscience Bulletin (2023)

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    Open Access

    Different TLR4 expression and microglia/macrophage activation induced by hemorrhage in the rat spinal cord after compressive injury

    Hemorrhage is a direct consequence of traumatic injury to the central nervous system and may cause innate immune reactions including cerebral Toll-like receptor (TLR) 4 upregulation which usually leads to poor...

    Yu-Kai Zhang, **-Tao Liu, Zheng-Wu Peng, Hong Fan in Journal of Neuroinflammation (2013)

  3. Article

    Open Access

    The effect of Lycium barbarum on spinal cord injury, particularly its relationship with M1 and M2 macrophage in rats

    Our past researches suggested that L. barbarum exhibits direct neuroprotective and immune regulatory effects on the central nervous system, which are highly related to the events involved in the spinal cord injur...

    Yu-Kai Zhang, Jian Wang, Ling Liu in BMC Complementary and Alternative Medicine (2013)

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    Article

    The Protective Effects of Inosine Against Chemical Hypoxia on Cultured Rat Oligodendrocytes

    Inosine is a purine nucleoside and is considered protective to neural cells including neurons and astrocytes against hypoxic injury. However, whether oligodendrocytes (OLs) could also be protected from hypoxia...

    Quan-Rui Ma, Hao Yang, **ang-Hui Zhao, Yu-Kai Zhang in Cellular and Molecular Neurobiology (2011)