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Article
Open AccessIdentification and characterization of endogenous biomarkers for hepatic vectorial transport (OATP1B3-P-gp) function using metabolomics with serum pharmacology
The organic anion-transporting polypeptide 1B3 and P-glycoprotein (P-gp) provide efficient directional transport (OATP1B3-P-gp) from the blood to the bile that serves as a key determinant of hepatic dispositio...
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Chapter and Conference Paper
Study on Modular Curriculums in Vocational Education and Training System
With the development policies and plans for vocational education appearing, modular curriculum in improving the vocational education and training system is more important to improve the education quality. The ...
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Article
Effect of concentration and adsorption time on the formation of a large-scale origami pattern
The arrangement of DNA-based nanostructures into the desired large-scale periodic pattern with the highest possible accuracy and control is essential for the DNA application in functional biomaterials; however...
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Article
The impact of drug transporters on adverse drug reaction
In this review, we have highlighted the adverse drug reaction mediated by transporters from two aspects: (1) competitive interactions between drug and drug/metabolite/endogenous substance mediated by transport...
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Article
Effects of pyridoxine on the intestinal absorption and pharmacokinetics of isoniazid in rats
Pyridoxine is always simultaneously administered orally with isoniazid for tuberculosis patients in the clinic to prevent or treat the nervous system side effects induced by isoniazid. So the aim of this resea...
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Article
Ethosomes, binary ethosomes and transfersomes of terbinafine hydrochloride: A comparative study
The aim of this study was to compare the skin permeation of ethosomes, binary ethosomes and transfersomes of Terbinafine Hydrochloride (TH) under non-occlusive conditions. These lipid vesicles were prepared an...
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Article
Synergistic penetration of ethosomes and lipophilic prodrug on the transdermal delivery of acyclovir
The aim of this study was to investigate the lipophilic prodrug as a means of promoting acyclovir (ACV) that exhibited biphasic insolubility into the ethosomes for optimum skin delivery. Acyclovir Palmitate (A...