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    Article

    Interventional radiologists have a higher rate of chromosomal damage due to occupational radiation exposure: a dicentric chromosome assay

    There are growing concerns regarding radiation exposure in medical workers who perform interventional fluoroscopy procedures. Owing to the nature of certain interventional procedures, workers may be subjected ...

    Younghyun Lee, Won ** Lee, Young Woo **, Seongjae Jang in European Radiology (2021)

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    Open Access

    Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

    Measurement of γ-H2AX foci levels in cells provides a sensitive and reliable method for quantitation of the radiation-induced DNA damage response. The objective of the present study was to develop a rapid, hig...

    Younghyun Lee, Qi Wang, Igor Shuryak, David J. Brenner in Radiation Oncology (2019)

  3. Article

    Open Access

    VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

    High linear energy transfer (LET) radiation such as carbon ion particles is successfully used for treatment of solid tumors. The reason why high LET radiation accomplishes greater tumor-killing than X-rays is ...

    Hiroshi Fujisawa, Nakako Izumi Nakajima, Shigeaki Sunada in Radiation Oncology (2015)