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  1. Article

    Open Access

    Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

    In genetically heterogeneous (UM-HET3) mice produced by the CByB6F1 × C3D2F1 cross, the Nrf2 activator astaxanthin (Asta) extended the median male lifespan by 12% (p = 0.003, log-rank test), while meclizine (Mec)...

    David E. Harrison, Randy Strong, Peter Reifsnyder, Nadia Rosenthal in GeroScience (2024)

  2. No Access

    Article

    An efficient parallel block coordinate descent algorithm for large-scale precision matrix estimation using graphics processing units

    Large-scale sparse precision matrix estimation has attracted wide interest from the statistics community. The convex partial correlation selection method (CONCORD) developed by Khare et al. (J R Stat Soc Ser B...

    Young-Geun Choi, Seunghwan Lee, Donghyeon Yu in Computational Statistics (2022)

  3. No Access

    Article

    Positive-definite modification of a covariance matrix by minimizing the matrix \(\ell_{\infty}\) norm with applications to portfolio optimization

    The covariance matrix, which should be estimated from the data, plays an important role in many multivariate procedures, and its positive definiteness (PDness) is essential for the validity of the procedures. ...

    Seonghun Cho, Shota Katayama, Johan Lim in AStA Advances in Statistical Analysis (2021)

  4. No Access

    Article

    Test for Uniformity of Exchangeable Random Variables on the Circle

    We are motivated by our laboratory experiment on the flocking behavior of termites. To test for the existence of flocking behavior, we revisit the problem to test uniform samples (with the samples uniformly di...

    Seonghun Cho, Young-Geun Choi, Johan Lim in Journal of the Korean Statistical Society (2021)

  5. No Access

    Article

    Discrimination between genetically identical peony roots from different regions of origin based on 1H-nuclear magnetic resonance spectroscopy-based metabolomics: determination of the geographical origins and estimation of the mixing proportions of blended samples

    Sixty peony root training samples of the same age were collected from various regions in Korea and China, and their genetic diversity was investigated for 23 chloroplast intergenic space regions. All samples w...

    Jung A Um, Young-Geun Choi, Dong-Kyu Lee in Analytical and Bioanalytical Chemistry (2013)

  6. No Access

    Chapter and Conference Paper

    Proactive Code Verification Protocol in Wireless Sensor Network

    For WSN(Wireless Sensor Network) to provide reliable service, authentication is one of the most important requirements. The authentication usually means the entity authentication, but owing to the data centric...

    Young-Geun Choi, Jeonil Kang, DaeHun Nyang in Computational Science and Its Applications… (2007)

  7. No Access

    Chapter and Conference Paper

    Certificate Issuing Using Proxy and Threshold Signatures in Self-initialized Ad Hoc Network

    In ad hoc network, it is very crucial to issue certificates safely in the self-initialized scheme where the system authority exists only at the beginning of the network operation. In order to solve this proble...

    Jeonil Kang, DaeHun Nyang in Computational Science and Its Applications… (2007)