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  1. Article

    Open Access

    A Tau PET tracer PBB3 binds to TMEM106B amyloid fibril in brain

    Qinyue Zhao, Yun Fan, Wanbing Zhao, You Ni, Youqi Tao, Jiang Bian… in Cell Discovery (2024)

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  2. No Access

    Article

    Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker and therapeutic target

    Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. At present, no definite ALS biomarkers are available. In this study, exosomes from the plasma of patients with ALS and healthy contr...

    Qinming Zhou, Lu He, ** Hu, Yining Gao, Dingding Shen, You Ni… in Frontiers of Medicine (2022)

  3. Article

    Open Access

    Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice

    Anti-IgLON5 disease is a rare neurological disorder associated with autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations with human IgLON5 antibodies have suggested an ant...

    You Ni, Yifan Feng, Dingding Shen, Ming Chen, **aona Zhu… in Journal of Neuroinflammation (2022)

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  4. Article

    Open Access

    A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?

    Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease involving both upper and lower motor neurons, leading to paralysis and eventually death. Symptomatic treatments such as inhibition...

    **aojiao Xu, Dingding Shen, Yining Gao, Qinming Zhou… in Translational Neurodegeneration (2021)

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  5. No Access

    Chapter

    Autophagy and Alzheimer’s Disease

    Alzheimer’s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in A...

    Sheng Chen, Qinming Zhou, You Ni, Weidong Le in Autophagy: Biology and Diseases (2020)