Skip to main content

5 Result(s)

within You Jia Xu Remove this filter Life Sciences Remove this filter

and

  1. No Access

    Article

    Hepcidin1 Knockout Mice Display Defects in Bone Microarchitecture and Changes of Bone Formation Markers

    Iron accumulation is a risk factor of osteoporosis; mechanisms leading to iron-related bone loss are not fully determined. We sought to better understand the effect of chronic iron accumulation on bone over t...

    Guang Si Shen, Qing Yang, **g Long Jian, Guo Yang Zhao… in Calcified Tissue International (2014)

  2. No Access

    Article

    Therapeutic Effect of Deferoxamine on Iron Overload-Induced Inhibition of Osteogenesis in a Zebrafish Model

    Osteoporosis results from an imbalance in bone remodeling, in which osteoclastic bone resorption exceeds osteoblastic bone formation. Iron has recently been recognized as an independent risk factor for osteopo...

    Bin Chen, Yi-Lin Yan, Chen Liu, Lin Bo, Guang-Fei Li… in Calcified Tissue International (2014)

  3. No Access

    Article

    Iron Overload Inhibits Osteoblast Biological Activity Through Oxidative Stress

    Iron overload has recently been connected with bone mineral density in osteoporosis. However, to date, the effect of iron overload on osteoblasts remains poorly understood. The purpose of this study is to exam...

    Yin-Feng He, Yong Ma, Chao Gao, Guo-yang Zhao… in Biological Trace Element Research (2013)

  4. No Access

    Article

    A Comparison of the Biological Activities of Human Osteoblast hFOB1.19 Between Iron Excess and Iron Deficiency

    Bone metabolism has a close relationship with iron homeostasis. To examine the effects of iron excess and iron deficiency on the biological activities of osteoblast in vitro, human osteoblast cells (hFOB1.19) ...

    Guo-yang Zhao, Li-** Zhao, Yin-feng He, Guang-Fei Li… in Biological Trace Element Research (2012)

  5. No Access

    Article

    Effect of hepcidin on intracellular calcium in human osteoblasts

    Hepcidin is known to increase intracellular iron through binding to and degrading ferroportin, which is a transmembrane protein that transports iron from the intracellular to the outside. However, it is not cl...

    Guang-Fei Li, You-Jia Xu, Yin-Feng He, Ben-Cai Du… in Molecular and Cellular Biochemistry (2012)