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  1. Article

    Open Access

    Individualized anemia management enhanced by ferric pyrophosphate citrate protocol

    The optimal use of erythropoiesis-stimulating agents (ESAs) and parenteral iron in managing anemia in end-stage renal disease (ESRD) remains controversial. One-size-fits-all rule-based algorithms dominate dosi...

    Yossi Chait, Brian H. Nathanson, Michael J. Germain in Scientific Reports (2022)

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  2. No Access

    Article

    Assessing accuracy of estimated dry weight in dialysis patients post transplantation: the kidney knows best

    Estimated dry weight is used to guide fluid removal during outpatient hemodialysis sessions. Errors in estimated dry weight can result in intradialytic hypotension and interdialytic fluid overload. The goal of...

    Michael J Germain, Barbara A Greco, Spencer Hodgins… in Journal of Nephrology (2021)

  3. No Access

    Article

    The Role of Feedback Control Design in Develo** Anemia Management Protocols

    The optimal use of erythropoiesis stimulating agents to treat anemia of end-stage renal disease remains difficult due to reported associations with adverse events. A patient’s hemoglobin response to these agen...

    Yossi Chait, Michael J. Germain, Christopher V. Hollot… in Annals of Biomedical Engineering (2021)

  4. No Access

    Article

    Models for the red blood cell lifespan

    The lifespan of red blood cells (RBCs) plays an important role in the study and interpretation of various clinical conditions. Yet, confusion about the meanings of fundamental terms related to cell survival an...

    Rajiv P. Shrestha, Joseph Horowitz… in Journal of Pharmacokinetics and Pharmacody… (2016)

  5. No Access

    Chapter and Conference Paper

    On establishing classic performance measures for reset control systems

    Reset controllers are linear controllers that reset some of their states to zero when their inputs reach a threshold. We are interested in their feedback connection with linear plants, and in this context, the...

    C. V. Hollot, Orhan Beker, Yossi Chait, Qian Chen in Perspectives in robust control (2001)

  6. No Access

    Chapter

    On The Stability of Control Systems Having Clegg Integrators

    In this paper, we consider control systems utilizing so-called Clegg integrators. A Clegg integrator is a linear integrator with reset mechanism whose describing function

    Hanzhong Hu, Yuan Zheng, Christopher V. Hollot… in Topics in Control and its Applications (1999)

  7. No Access

    Chapter and Conference Paper

    Parametric robust control by quantitative feedback theory

    The problem of performance robustness, especially in the face of significant parametric uncertainty, has been increasingly recognized as a predominant issue of engineering significance in many design applicati...

    Osita Nwokah, Suhada Jayasuriya, Yossi Chait in Mechanics and Control (1992)